ATM activation accompanies histone H2AX phosphorylation in A549 cells upon exposure to tobacco smoke.
about
DNA damage signaling assessed in individual cells in relation to the cell cycle phase and induction of apoptosisgammaH2AX: A potential DNA damage response biomarker for assessing toxicological risk of tobacco productsDNA damage response induced by tobacco smoke in normal human bronchial epithelial and A549 pulmonary adenocarcinoma cells assessed by laser scanning cytometryCellular senescence in normal and premature lung aging.Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cellsInduction of DNA damage response by the supravital probes of nucleic acids.Cytometric analysis of DNA damage: phosphorylation of histone H2AX as a marker of DNA double-strand breaks (DSBs).Molecular processes that drive cigarette smoke-induced epithelial cell fate of the lung.Ataxia telangiectasia mutated- and Rad3-related kinase drives both the early and the late DNA-damage response to the monofunctional antitumour alkylator S23906.Analysis of individual molecular events of DNA damage response by flow- and image-assisted cytometryParacrine potential of fibroblasts exposed to cigarette smoke extract with vascular growth factor inductionDNA damage and DNA damage responses in THP-1 monocytes after exposure to spores of either Stachybotrys chartarum or Aspergillus versicolor or to T-2 toxin.DNA damage signaling is activated during cancer progression in human colorectal carcinoma.The checkpointkinase 2 (CHK2) 1100delC germ line mutation is not associated with the development of squamous cell carcinoma of the head and neck (SCCHN).Characterisation of an aerosol exposure system to evaluate the genotoxicity of whole mainstream cigarette smoke using the in vitro γH2AX assay by high content screeningDouble-strand break damage and associated DNA repair genes predispose smokers to gene methylation.Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN.The β-carboline alkaloid harmine inhibits telomerase activity of MCF-7 cells by down-regulating hTERT mRNA expression accompanied by an accelerated senescent phenotype.Effects of side-stream tobacco smoke and smoke extract on glutathione- and oxidative DNA damage repair-deficient mice and blood cellsDNA damage response induced by exposure of human lung adenocarcinoma cells to smoke from tobacco- and nicotine-free cigarettes.Biscoclaurine alkaloid cepharanthine protects DNA in TK6 lymphoblastoid cells from constitutive oxidative damage.SIRT1 pathway dysregulation in the smoke-exposed airway epithelium and lung tumor tissue.Administration of ON 01210.Na after exposure to ionizing radiation protects bone marrow cells by attenuating DNA damage response.Genetic ablation of histone deacetylase 2 leads to lung cellular senescence and lymphoid follicle formation in COPD/emphysema.In vitro assessment of the role of DpC in the treatment of head and neck squamous cell carcinoma.
P2860
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P2860
ATM activation accompanies histone H2AX phosphorylation in A549 cells upon exposure to tobacco smoke.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
ATM activation accompanies his ...... pon exposure to tobacco smoke.
@en
type
label
ATM activation accompanies his ...... pon exposure to tobacco smoke.
@en
prefLabel
ATM activation accompanies his ...... pon exposure to tobacco smoke.
@en
P2093
P2860
P356
P1433
P1476
ATM activation accompanies his ...... pon exposure to tobacco smoke.
@en
P2093
Anthony P Albino
Diana Gietl
Ellen Jorgensen
Toshiki Tanaka
Xuan Huang
P2860
P2888
P356
10.1186/1471-2121-8-26
P577
2007-06-26T00:00:00Z
P5875
P6179
1011977412