The adenovirus E1A transforming protein activates the proliferating cell nuclear antigen promoter via an activating transcription factor site.
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The adenovirus E1A-regulated transcription factor E4F is generated from the human homolog of nuclear factor phiAP3Human papillomavirus E6 proteins bind p53 in vivo and abrogate p53-mediated repression of transcriptionp53-mediated regulation of proliferating cell nuclear antigen expression in cells exposed to ionizing radiationInduction of AP-1 DNA-binding activity and c-fos mRNA by the adenovirus 243R E1A protein and cyclic AMP requires domains necessary for transformation.The human papillomavirus type 16 E7 gene product interacts with and trans-activates the AP1 family of transcription factorsTranscriptional activation of the human proliferating-cell nuclear antigen promoter by p53.Regulation of the human proliferating cell nuclear antigen promoter by the adenovirus E1A-associated protein p107Transcription factors RFX1/EF-C and ATF-1 associate with the adenovirus E1A-responsive element of the human proliferating cell nuclear antigen promoter.Human T-cell leukemia virus type 1 Tax transactivates the human proliferating cell nuclear antigen promoter.Transcriptional coactivator cAMP response element binding protein mediates induction of the human proliferating cell nuclear antigen promoter by the adenovirus E1A oncoprotein.Domains A and B in the Rb pocket interact to form a transcriptional repressor motif.The Rb family contains a conserved cyclin-dependent-kinase-regulated transcriptional repressor motifConstitutive activation of gene expression by thyroid hormone receptor results from reversal of p53-mediated repression.The adenovirus E1A 12S product displays functional redundancy in activating the human proliferating cell nuclear antigen promoterModulation of transcriptional activation of the proliferating cell nuclear antigen promoter by the adenovirus E1A 243-residue oncoprotein depends on proximal activatorsA complex promoter element mediates transactivation of the human proliferating cell nuclear antigen promoter by the 243-residue adenovirus E1A oncoproteinPromoter-specific trans-activation by the adenovirus E1A12S product involves separate E1A domainsCREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription.Promoter activity of the proliferating-cell nuclear antigen gene is associated with inducible CRE-binding proteins in interleukin 2-stimulated T lymphocytes.The CR1 and CR3 domains of the adenovirus type 5 E1A proteins can independently mediate activation of ATF-2.YY1 and NF1 both activate the human p53 promoter by alternatively binding to a composite element, and YY1 and E1A cooperate to amplify p53 promoter activityRepression of RNA polymerase III transcription by adenovirus E1A.Modulation of cellular and viral promoters by mutant human p53 proteins found in tumor cells.Coordinated trans activation of DNA synthesis- and precursor-producing enzymes by polyomavirus large T antigen through interaction with the retinoblastoma protein.Activation of the mouse proliferating cell nuclear antigen gene promoter by adenovirus type 12 E1A proteins.
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P2860
The adenovirus E1A transforming protein activates the proliferating cell nuclear antigen promoter via an activating transcription factor site.
description
1991 nî lūn-bûn
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1991年の論文
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1991年学术文章
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1991年学术文章
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1991年学术文章
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1991年学术文章
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1991年学术文章
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1991年學術文章
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1991年學術文章
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1991年學術文章
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name
The adenovirus E1A transformin ...... ing transcription factor site.
@en
type
label
The adenovirus E1A transformin ...... ing transcription factor site.
@en
prefLabel
The adenovirus E1A transformin ...... ing transcription factor site.
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P2860
P1433
P1476
The adenovirus E1A transformin ...... ting transcription factor site
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P2093
G F Morris
M B Mathews
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1991-12-01T00:00:00Z