Tunicamycin sensitizes human melanoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by up-regulation of TRAIL-R2 via the unfolded protein response.
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A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycinMelanoma and the Unfolded Protein ResponseEndoplasmic reticulum stress-mediated pathways to both apoptosis and autophagy: Significance for melanoma treatmentDepolarization Controls TRAIL-Sensitization and Tumor-Selective Killing of Cancer Cells: Crosstalk with ROSHepatitis C Virus Infection Induces Apoptosis through a Bax-Triggered, Mitochondrion-Mediated, Caspase 3-Dependent PathwayGeneral Sensitization of melanoma cells for TRAIL-induced apoptosis by the potassium channel inhibitor TRAM-34 depends on release of SMACTrailing TRAIL Resistance: Novel Targets for TRAIL Sensitization in Cancer CellsBid participates in genotoxic drug-induced apoptosis of HeLa cells and is essential for death receptor ligands' apoptotic and synergistic effectsDevelopment of an anti-angiogenic therapeutic model combining scAAV2-delivered siRNAs and noninvasive photoacoustic imaging of tumor vasculature development2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human melanoma cells through XBP-1-mediated up-regulation of TRAIL-R2Antitumor agent 25-epi Ritterostatin GN1N induces endoplasmic reticulum stress and autophagy mediated cell death in melanoma cellsTNFα cooperates with IFN-γ to repress Bcl-xL expression to sensitize metastatic colon carcinoma cells to TRAIL-mediated apoptosis.Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and BortezomibDual processing of FAT1 cadherin protein by human melanoma cells generates distinct protein productsUtilization of the cellular stress response to sensitize cancer cells to TRAIL-mediated apoptosis.Medicarpin, a legume phytoalexin sensitizes myeloid leukemia cells to TRAIL-induced apoptosis through the induction of DR5 and activation of the ROS-JNK-CHOP pathway.Casticin potentiates TRAIL-induced apoptosis of gastric cancer cells through endoplasmic reticulum stress.Blockade of GRP78 sensitizes breast cancer cells to microtubules-interfering agents that induce the unfolded protein response.RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy.A promising "TRAIL" of tanshinones for cancer therapy.Selenium for the prevention of cutaneous melanoma.Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent inducing cell cycle arrest and sensitization to TRAIL in cancer cells.Chemotherapeutic sensitization by endoplasmic reticulum stress: increasing the efficacy of taxane against prostate cancer.Human melanoma cells under endoplasmic reticulum stress are more susceptible to apoptosis induced by the BH3 mimetic obatoclax.hvTRA, a novel TRAIL receptor agonist, induces apoptosis and sustained growth retardation in melanoma.Emerging targets for combination therapy in melanomas.Modulation of CCAAT/enhancer binding protein homologous protein (CHOP)-dependent DR5 expression by nelfinavir sensitizes glioblastoma multiforme cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).Glucose Deprivation Induces ATF4-Mediated Apoptosis through TRAIL Death Receptors.The DeISGylase USP18 limits TRAIL-induced apoptosis through the regulation of TRAIL levels: Cellular levels of TRAIL influences responsiveness to TRAIL-induced apoptosis.ROS-dependent phosphorylation of Bax by wortmannin sensitizes melanoma cells for TRAIL-induced apoptosis.Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of BaxER stress sensitizes cells to TRAIL through down-regulation of FLIP and Mcl-1 and PERK-dependent up-regulation of TRAIL-R2.Type I IFNs signaling and apoptosis resistance in glioblastoma cells.Glucose-regulated protein 78 antagonizes cisplatin and adriamycin in human melanoma cells.Structure-activity relationship of Triterpenes and derived Glycosides against cancer cells and mechanism of apoptosis induction.Down-Regulation of Survivin by Nemadipine-A Sensitizes Cancer Cells to TRAIL-Induced Apoptosis.Depolarization potentiates TRAIL-induced apoptosis in human melanoma cells: role for ATP-sensitive K+ channels and endoplasmic reticulum stress.BRAF/MEK inhibitors promote CD47 expression that is reversible by ERK inhibition in melanoma.The unfolded protein response in melanocytes: activation in response to chemical stressors of the endoplasmic reticulum and tyrosinase misfolding.Secretory stressors induce intracellular death receptor accumulation to control apoptosis.
P2860
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P2860
Tunicamycin sensitizes human melanoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by up-regulation of TRAIL-R2 via the unfolded protein response.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Tunicamycin sensitizes human m ...... the unfolded protein response.
@en
type
label
Tunicamycin sensitizes human m ...... the unfolded protein response.
@en
prefLabel
Tunicamycin sensitizes human m ...... the unfolded protein response.
@en
P2093
P1433
P1476
Tunicamycin sensitizes human m ...... the unfolded protein response.
@en
P2093
Chen Chen Jiang
Kelly A Kiejda
Li Hua Chen
Nizar Mhaidat
Peter Hersey
Rick Thorne
Susan Gillespie
Yu Fang Wang
P304
P356
10.1158/0008-5472.CAN-07-0213
P407
P577
2007-06-01T00:00:00Z