Identification of a key pathway required for the sterile inflammatory response triggered by dying cells.
about
Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1βInterleukin-1 in the pathogenesis and treatment of inflammatory diseasesIL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin GDifferential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammationThe IL-1-like cytokine IL-33 is inactivated after maturation by caspase-1Exploring the full spectrum of macrophage activationFibrosis biomarkers in workers exposed to MWCNTsMechanisms underlying skin disorders induced by EGFR inhibitorsSTAT3, a Key Parameter of Cytokine-Driven Tissue Protection during Sterile Inflammation - the Case of Experimental Acetaminophen (Paracetamol)-Induced Liver DamageThe IL-1 cytokine family and its role in inflammation and fibrosis in the lungInflammasome/IL-1β Responses to Streptococcal PathogensThe role of IL-33 and mast cells in allergy and inflammationMechanisms of epithelial wound detectionIL-1α/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in miceDamage-associated molecular patterns in cancer: a double-edged swordMacrophage in chronic kidney diseaseMicroRNA29a regulates IL-33-mediated tissue remodelling in tendon diseaseMolecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistanceMyD88 dependence of beryllium-induced dendritic cell trafficking and CD4⁺ T-cell primingCD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammationThe Reduction of Peripheral Blood CD4+ T Cell Indicates Persistent Organ Failure in Acute PancreatitisOzone exposure of macrophages induces an alveolar epithelial chemokine response through IL-1alphaIntracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammationInflammation-a Critical Appreciation of the Role of Myeloid CellsNeutrophils in a mouse model of autoantibody-mediated arthritis: critical producers of Fc receptor gamma, the receptor for C5a, and lymphocyte function-associated antigen 1How dying cells alert the immune system to dangerCrucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvantsNLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystalsSterile inflammation: sensing and reacting to damagePromising therapies for treatment of nonalcoholic steatohepatitis.Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease.Dynamics of neutrophil migration in lymph nodes during infection.IL-1α is a DNA damage sensor linking genotoxic stress signaling to sterile inflammation and innate immunity.Development of a spontaneous liver disease resembling autoimmune hepatitis in mice lacking tyro3, axl and mer receptor tyrosine kinasesC4b-binding protein is present in affected areas of myocardial infarction during the acute inflammatory phase and covers a larger area than C3.Updates on the pathophysiology and management of acne rosacea.Cytokine inhibition in the treatment of COPD.A novel hybrid adenoretroviral vector with more extensive E3 deletion extends transgene expression in submandibular glands.Conditional deletion of IkappaB-kinase-beta accelerates helicobacter-dependent gastric apoptosis, proliferation, and preneoplasia.Potential of IL-1, IL-18 and Inflammasome Inhibition for the Treatment of Inflammatory Skin Diseases.
P2860
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P2860
Identification of a key pathway required for the sterile inflammatory response triggered by dying cells.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Identification of a key pathwa ...... onse triggered by dying cells.
@en
type
label
Identification of a key pathwa ...... onse triggered by dying cells.
@en
prefLabel
Identification of a key pathwa ...... onse triggered by dying cells.
@en
P2093
P2860
P356
P1433
P1476
Identification of a key pathwa ...... onse triggered by dying cells.
@en
P2093
Chun-Jen Chen
Douglas Golenbock
George Reed
Hajime Kono
Kenneth L Rock
P2860
P2888
P304
P356
10.1038/NM1603
P407
P50
P577
2007-06-17T00:00:00Z