Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke. - Wikidata - awgldk - TriplyDB

Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke.

Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke.

http://www.wikidata.org/entity/Q40119775

about

Tissue-type plasminogen activator is a neuroprotectant in the central nervous system The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-methyl-D-aspartate receptors Targeting therapeutics across the blood brain barrier (BBB), prerequisite towards thrombolytic therapy for cerebrovascular disorders-an overview and advancements Clinical Implications of Sulcal Enhancement on Postcontrast Fluid Attenuated Inversion Recovery Images in Patients with Acute Stroke Symptoms Genome response to tissue plasminogen activator in experimental ischemic stroke Blood-brain barrier disruption in humans is independently associated with increased matrix metalloproteinase-9.Translational pharmacokinetics: challenges of an emerging approach to drug development in stroke.Novel frontiers in ultra-structural and molecular MRI of the brain Plasmin-dependent modulation of the blood-brain barrier: a major consideration during tPA-induced thrombolysis?Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors.Understanding IMS III: old data shed new light on a futile trial.Hyperacute injury marker (HARM) in primary hemorrhage: a distinct form of CNS barrier disruption.Admission CT perfusion is an independent predictor of hemorrhagic transformation in acute stroke with similar accuracy to DWI.Desmoteplase: discovery, insights and opportunities for ischaemic stroke.Tissue-type plasminogen activator has a neuroprotective effect in the ischemic brain mediated by neuronal TNF-α.Plasma tPA-Activity and Progression of Cerebral White Matter Hyperintensities in Lacunar Stroke Patients.Endothelial cells and astrocytes: a concerto en duo in ischemic pathophysiology.Evidence-based changes in devices and methods of endovascular recanalization therapy Tissue-type plasminogen activator regulates the neuronal uptake of glucose in the ischemic brain.Signaling, delivery and age as emerging issues in the benefit/risk ratio outcome of tPA For treatment of CNS ischemic disorders.The usefulness of compliant balloon for recanalization of acute ischemic stroke.Blood-brain barrier disruption after cardiac surgery.Importance of Contrast-Enhanced Fluid-Attenuated Inversion Recovery Magnetic Resonance Imaging in Various Intracranial Pathologic Conditions Diverse roles of matrix metalloproteinases and tissue inhibitors of metalloproteinases in neuroinflammation and cerebral ischemia.Tissue Plasminogen Activator Neurotoxicity is Neutralized by Recombinant ADAMTS 13 The low-density lipoprotein receptor-related protein 1 mediates tissue-type plasminogen activator-induced microglial activation in the ischemic brain Age and albumin D site-binding protein control tissue plasminogen activator levels: neurotoxic impact.Alteplase treatment does not increase brain injury after mechanical middle cerebral artery occlusion in the rat.Hemorrhagic transformation after ischemic stroke in animals and humans Plasminogen activation and thrombolysis for ischemic stroke.Alteplase: a review of its use in the management of acute ischaemic stroke.Post-carotid stenting reperfusion injury with blood-brain barrier disruption on gadolinium-enhanced FLAIR MRI.Does the use of IV tPA in the current era of rapid and predictable recanalization by mechanical embolectomy represent good value?tPA Modulation of the Blood-Brain Barrier: A Unifying Explanation for the Pleiotropic Effects of tPA in the CNS.Xenon is an inhibitor of tissue-plasminogen activator: adverse and beneficial effects in a rat model of thromboembolic stroke Editorial: The Role of the Plasminogen Activating System in Neurobiology.Worse Outcome in Stroke Patients Treated with rt-PA Without Early Reperfusion: Associated Factors.Blood-brain barrier leakage increases with small vessel disease in acute ischemic stroke.Tissue plasminogen activator-based nanothrombolysis for ischemic stroke.Endovascular Reperfusion and Cooling in Cerebral Acute Ischemia (ReCCLAIM I).

P2860

Q26782904-E61803AF-EB2C-42DA-B4B3-DC2C4C8F3A68 Q28771352-92ADA33B-7666-4B16-91DF-0589E08EA0D0 Q30393215-80048034-E176-4887-AC19-60E9C6FC01FF Q30980457-BE41B194-E607-4A86-9DA1-8D570DACE389 Q33560492-62BEE7A8-8C25-48BE-ABEC-D9EF375824C5 Q33684529-BD6B75B4-12F2-494C-9FAF-A9BC5976BEA6 Q33882182-5404288E-5A7F-4769-8266-9DE9DBE3549E Q33953354-EF1E9868-1614-416D-8372-4F97350F1DEF Q34018715-B632929E-9380-4D9A-9629-47E669F4D971 Q34168098-62701E97-3C80-48EC-8886-3EB395B15592 Q34498039-DE94CC24-274A-4A51-BCDE-CFC73BDC3152 Q35529945-A6B32EED-3537-4473-BA27-9A4F3B5954F6 Q35649425-601456CD-D58A-4CB9-A5DD-61DAC41AA943 Q35657910-C45929BE-193C-413E-8522-017FE7AECA25 Q35880850-3274FEEA-A370-40F7-8061-CA98F01308B4 Q35945812-D7FE706D-4624-45EB-87F1-F5925B79897D Q36072867-8B933C0C-A3B2-4487-8CF0-CDD84D8C7481 Q36195764-38EFC493-31D6-478F-8DC1-8328BC8680EA Q36222327-AFC19524-A1B5-4E5F-A477-AD023CAE945B Q36307742-A737CA2B-30F9-4453-99F3-03A1D292482F Q36377513-617D51E8-9E96-4DAA-9BBE-1D1AD724E836 Q36431467-A86BCCDC-F12A-405D-A9DC-876B45020017 Q36484883-EE7466F0-C509-4B8C-8A9C-63AEA915DDC6 Q36644315-B5CA05B0-121C-4C4D-98B2-6C703F94F747 Q36903087-84E3E01D-9D1E-4A73-A5F5-6C03298246C3 Q37071903-0CCE60B1-B1EC-4B20-9171-56B117465904 Q37270632-3D675C69-4591-4CA4-9ACB-0CB730CEEFB3 Q37298322-CE2C5E72-5758-4F5C-820A-940D78A70AD8 Q37559355-CC915B5A-18CA-4077-A7F2-9F5960E02A12 Q37998537-ED9C9B5F-F680-442C-9DE9-9D2EF59BB1AB Q38040823-7A52EB70-755F-42FA-A891-5E1F4CDC9949 Q38434319-4800B230-1BA3-4CA2-BE75-FCC6546A355D Q38693987-EA0D2C91-AD31-4D5C-9FFF-071484CB0DAE Q38965982-8CC30CCE-4A5E-496E-9118-6EBA85989B95 Q39908525-8A2DF86A-9A87-43C8-A76D-416B4FC3E789 Q42388151-02BDAD5E-93D8-465F-A7CA-E46276FAE930 Q47223299-8253C277-5EF0-4CC3-93CB-239A9C72509F Q47717834-954752C7-92F4-42A5-9BBD-002AA0D627AA Q47931181-7A16F972-BD11-4FD9-9533-0352F33B5BA5 Q48136167-95690848-1930-4783-BB7E-67D00ADDC7E0

P2860

Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke.

http://www.wikidata.org/entity/Q40119775

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年学术文章

@wuu

2008年学术文章

@zh-cn

2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh

2008年學術文章

@zh-hant

name

Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke.

@en

type

label

Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke.

@en

prefLabel

Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke.

@en

P1433

Q40119775-C5AC7BF3-8A4E-4980-AAD5-AE0992091C84

P1476

Q40119775-78E65D1D-5B9A-42DC-B24C-3D606C24CA60

P2093

Q40119775-238E15CF-DAB6-41FD-8116-5FF6B9578436

Q40119775-3150A04D-FF27-41B6-B070-3CC9F122895A

Q40119775-39EFC0FD-D059-43A3-9700-34AB7881A2FC

Q40119775-53D00C1F-D3BE-4C28-BCC5-767E0F809FAC

Q40119775-5A99FF64-3E4F-4944-8D5D-7473E375F77A

Q40119775-70E0B1F4-B15C-4DFA-A53B-C63484F5A32E

Q40119775-ABC5C44C-39C6-4BCC-AC96-5A8D2EE5D5A1

Q40119775-D6C47BD1-90CC-41CB-939A-C692CFAD7292

Q40119775-E99677A1-10A5-43C6-B34A-DB35389AC17E

P2860

Q40119775-06B027CF-9D15-44AE-A20F-08C1BA24CE3A

Q40119775-08843A01-1861-418F-8A0B-07E268A889C7

Q40119775-151B8141-8BDC-428E-A6C0-58824A784550

Q40119775-2F9C82E5-7841-467D-9719-FD01A14BF918

Q40119775-4348DD50-6B05-4C79-8909-01D8F3619E55

Q40119775-55B4FBE5-03EF-4EB8-9791-7ACAA428B91C

Q40119775-6625C3CE-C89A-4CA8-AC1A-AE03B168FE8B

Q40119775-7BA94DD4-6BD6-4CB0-B33B-D3D65D94396A

Q40119775-974C0340-DD85-4B70-A6BD-DC43796D4D4F

Q40119775-97C18005-C1B3-430E-8078-1196B50CB474

P304

Q40119775-B9E51BD6-548C-4AF6-A89E-1AA39725E751

P31

Q40119775-4D21ADDC-9F20-487C-8B47-49C5C22A701E

P356

Q40119775-68A13F70-12DA-497A-9C99-BD9DBEAA566D

P433

Q40119775-F9694997-AFCA-4699-A302-BFAE3E57F445

P478

Q40119775-85A95147-D7B1-4D5E-AFB4-0566E80CD246

P50

Q40119775-390861E8-21CB-40EF-99CC-F7AB64B1E203

Q40119775-F75068D7-6AC0-4FA4-B80D-657F5492BBB8

P577

Q40119775-380265C1-5BC1-496D-8B40-48BF5543FE71

P698

Q40119775-3A07159A-4DE1-4B5D-BA23-BECA890DB654

P921

Q40119775-8C2C14A7-C32B-48A0-9AB6-DACBBEE85624

Q40119775-C24EE5ED-50C7-4252-8388-FB120A46F6DA

P356

P1433

Cerebrovascular Diseases

P1476

Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke.

@en

P2093

Chelsea S Kidwell

http://www.w3.org/2001/XMLSchema#string

Fernando Vinuela

http://www.w3.org/2001/XMLSchema#string

Gary Duckwiler

http://www.w3.org/2001/XMLSchema#string

Jeffry R Alger

http://www.w3.org/2001/XMLSchema#string

Larry Latour

http://www.w3.org/2001/XMLSchema#string

Reza Jahan

http://www.w3.org/2001/XMLSchema#string

Sidney Starkman

http://www.w3.org/2001/XMLSchema#string

Steven Warach

http://www.w3.org/2001/XMLSchema#string

UCLA Thrombolysis Investigators

http://www.w3.org/2001/XMLSchema#string

P2860

Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial

Tissue plasminogen activator for acute ischemic stroke

Quantitative evaluation of BBB permeability after embolic stroke in rat using MRI.

The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.

The neurotoxicity of tissue plasminogen activator?

Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice.

Predictors of hemorrhagic transformation in patients receiving intra-arterial thrombolysis.

Involvement of matrix metalloproteinase in thrombolysis-associated hemorrhagic transformation after embolic focal ischemia in rats.

Closure of the blood-brain barrier by matrix metalloproteinase inhibition reduces rtPA-mediated mortality in cerebral ischemia with delayed reperfusion.

Guidelines for the early management of patients with ischemic stroke: A scientific statement from the Stroke Council of the American Stroke Association.

P304

338-343

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1159/000118379

http://www.w3.org/2001/XMLSchema#string

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

25

http://www.w3.org/2001/XMLSchema#string

P50

Jeffrey L. Saver

P577

2008-02-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

18303253

http://www.w3.org/2001/XMLSchema#string

P921

blood–brain barrier