A large-tumor-antigen-specific monoclonal antibody inhibits DNA replication of simian virus 40 minichromosomes in an in vitro elongation system.
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DNA helicase activity of SV40 large tumor antigenActivation of CREB/ATF sites by polyomavirus large T antigen.Renaturation and DNA looping promoted by the SV40 large tumour antigen.Simian virus 40 (SV40) DNA replication: SV40 large T antigen unwinds DNA containing the SV40 origin of replication.Replication of simian virus 40 origin-containing DNA in vitro with purified proteinsInitiation of simian virus 40 DNA replication in vitro: large-tumor-antigen- and origin-dependent unwinding of the template.Topoisomerase activity is associated with purified SV40 T antigenAnalysis of a large-T-antigen variant expressed in simian virus 40-transformed mouse cell line mKS-A.Protein domains connect cell cycle stimulation directly to initiation of DNA replication.Viral DNA synthesis in nonpermissive rat F-111 cells and its role in neoplastic transformation by polyomavirusHelicase, DNA-binding, and immunological properties of replication-defective simian virus 40 mutant T antigens.Activation of ATPase activity of simian virus 40 large T antigen by the covalent affinity analog of ATP, fluorosulfonylbenzoyl 5'-adenosineCamptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks.Thermally inactivated simian virus 40 tsA58 mutant T antigen cannot initiate viral DNA replication in vitroThree domains in the simian virus 40 core origin orchestrate the binding, melting, and DNA helicase activities of T antigen.Differential increase in topoisomerase II in simian virus 40-infected cells.Large T-antigen mutants define multiple steps in the initiation of simian virus 40 DNA replicationPhosphorylation of polyomavirus large T antigen: effects of viral mutations and cell growth state.Unwinding of chromatin by the SV40 large T antigen DNA helicase.Recognition mechanisms in the synthesis of animal virus DNA.Two conditional tsA mutant simian virus 40 T antigens display marked differences in thermal inactivation.Simian virus 40 T-antigen DNA helicase is a hexamer which forms a binary complex during bidirectional unwinding from the viral origin of DNA replication.Effects of in vitro dephosphorylation on DNA-binding and DNA helicase activities of simian virus 40 large tumor antigen.Monoclonal antibodies as probes for a function of large T antigen during the elongation process of simian virus 40 DNA replication.Specific interaction of simian virus 40 large T antigen with cellular chromatin and nuclear matrix during the course of infection.Application of an immunoprecipitation procedure to the study of SV40 tumor antigen interaction with mouse genomic DNA sequences.Sequence independent duplex DNA opening reaction catalysed by SV40 large tumor antigenEffects of VM26, a specific inhibitor of type II DNA topoisomerase, on SV40 chromatin replication in vitro.Transfer of nucleosomes from parental to replicated chromatin.Inhibition of DNA synthesis by aphidicolin induces supercoiling in simian virus 40 replicative intermediates
P2860
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P2860
A large-tumor-antigen-specific monoclonal antibody inhibits DNA replication of simian virus 40 minichromosomes in an in vitro elongation system.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年論文
@yue
1985年論文
@zh-hant
1985年論文
@zh-hk
1985年論文
@zh-mo
1985年論文
@zh-tw
1985年论文
@wuu
1985年论文
@zh
1985年论文
@zh-cn
name
A large-tumor-antigen-specific ...... an in vitro elongation system.
@en
type
label
A large-tumor-antigen-specific ...... an in vitro elongation system.
@en
prefLabel
A large-tumor-antigen-specific ...... an in vitro elongation system.
@en
P2093
P2860
P1433
P1476
A large-tumor-antigen-specific ...... an in vitro elongation system
@en
P2093
P2860
P304
P407
P577
1985-05-01T00:00:00Z