Perforin-dependent cryptococcal microbicidal activity in NK cells requires PI3K-dependent ERK1/2 signaling.
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Signaling in Effector Lymphocytes: Insights toward Safer ImmunotherapyCryptococcal interactions with the host immune system.Ras-related C3 Botulinum Toxin Substrate (Rac) and Src Family Kinases (SFK) Are Proximal and Essential for Phosphatidylinositol 3-Kinase (PI3K) Activation in Natural Killer (NK) Cell-mediated Direct Cytotoxicity against Cryptococcus neoformans.An acidic microenvironment increases NK cell killing of Cryptococcus neoformans and Cryptococcus gattii by enhancing perforin degranulation.Memory CD4+ T cells are required for optimal NK cell effector functions against the opportunistic fungal pathogen Pneumocystis murina.Role of perforin-mediated cell apoptosis in murine models of infusion-induced bone marrow failure.Innate immune cell response upon Candida albicans infectionRequirement and redundancy of the Src family kinases Fyn and Lyn in perforin-dependent killing of Cryptococcus neoformans by NK cellsDirect microbicidal activity of cytotoxic T-lymphocytes.Mechanisms of cryptococcal virulence and persistence.Experimental models of cryptococcosis.Activation of natural killer cells during microbial infectionsImmunity to Cryptococcus neoformans and C. gattii during cryptococcosisInnate host defenses against Cryptococcus neoformans.Granule-Dependent Natural Killer Cell Cytotoxicity to Fungal Pathogens.Cryptococcus neoformans directly stimulates perforin production and rearms NK cells for enhanced anticryptococcal microbicidal activity.Innate Immune Responses to Cryptococcus.Involvement of ERK1/2, p38 and PI3K in megakaryocytic differentiation of K562 cells.Enhanced innate immune responsiveness to pulmonary Cryptococcus neoformans infection is associated with resistance to progressive infection.NK-cell dysfunction in human renal carcinoma reveals diacylglycerol kinase as key regulator and target for therapeutic intervention.Defective phosphorylation of interleukin-18 receptor beta causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis.
P2860
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P2860
Perforin-dependent cryptococcal microbicidal activity in NK cells requires PI3K-dependent ERK1/2 signaling.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Perforin-dependent cryptococca ...... 3K-dependent ERK1/2 signaling.
@en
type
label
Perforin-dependent cryptococca ...... 3K-dependent ERK1/2 signaling.
@en
prefLabel
Perforin-dependent cryptococca ...... 3K-dependent ERK1/2 signaling.
@en
P2093
P1476
Perforin-dependent cryptococca ...... 3K-dependent ERK1/2 signaling.
@en
P2093
Christopher H Mody
Gareth J Jones
Jeremy C D Wiseman
Kaleb J Marr
Ling Ling Ma
P304
P356
10.4049/JIMMUNOL.178.10.6456
P407
P577
2007-05-01T00:00:00Z