about
A human-curated annotation of the Candida albicans genome.Emerging Threats in Antifungal-Resistant Fungal PathogensNovel Approaches for Fungal Transcriptomics from Host SamplesTipping the balance both ways: drug resistance and virulence in Candida glabrataGain of function mutations in CgPDR1 of Candida glabrata not only mediate antifungal resistance but also enhance virulenceThe bZIP transcription factor Rca1p is a central regulator of a novel CO₂ sensing pathway in yeast.Candida yeast long chain fatty alcohol oxidase is a c-type haemoprotein and plays an important role in long chain fatty acid metabolismHigh-Resolution Genetics Identifies the Lipid Transfer Protein Sec14p as Target for Antifungal ErgolinesIdentification and characterization of a Cryptococcus neoformans ATP binding cassette (ABC) transporter-encoding gene, CnAFR1, involved in the resistance to fluconazole.A novel multidrug efflux transporter gene of the major facilitator superfamily from Candida albicans (FLU1) conferring resistance to fluconazole.Genetic separation of FK506 susceptibility and drug transport in the yeast Pdr5 ATP-binding cassette multidrug resistance transporter.Divergent functions of three Candida albicans zinc-cluster transcription factors (CTA4, ASG1 and CTF1) complementing pleiotropic drug resistance in Saccharomyces cerevisiae.MALDI-TOF MS-based drug susceptibility testing of pathogens: the example of Candida albicans and fluconazole.TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2.Fluconazole plus cyclosporine: a fungicidal combination effective against experimental endocarditis due to Candida albicans.Isolation and characterization of a secreted metalloprotease of Aspergillus fumigatus.Novel acid phosphatase in Candida glabrata suggests selective pressure and niche specialization in the phosphate signal transduction pathway.Identification and expression of multidrug transporters responsible for fluconazole resistance in Candida dubliniensisSecreted aspartyl proteinases and interactions of Candida albicans with human endothelial cells.Genetic dissection of azole resistance mechanisms in Candida albicans and their validation in a mouse model of disseminated infectionContribution of CgPDR1-regulated genes in enhanced virulence of azole-resistant Candida glabrataGenome-wide expression profiling of the response to short-term exposure to fluconazole in Cryptococcus neoformans serotype AThe ATP binding cassette transporter gene CgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents.Experimental induction of fluconazole resistance in Candida tropicalis ATCC 750Sensitive bioassay for determination of fluconazole concentrations in plasma using a Candida albicans mutant hypersusceptible to azoles.Role of ATP-binding-cassette transporter genes in high-frequency acquisition of resistance to azole antifungals in Candida glabrata.Prevalence of molecular mechanisms of resistance to azole antifungal agents in Candida albicans strains displaying high-level fluconazole resistance isolated from human immunodeficiency virus-infected patientsEvolution of drug resistance in experimental populations of Candida albicans.Germ tubes and proteinase activity contribute to virulence of Candida albicans in murine peritonitisIn vivo systematic analysis of Candida albicans Zn2-Cys6 transcription factors mutants for mice organ colonization.Farnesol-induced apoptosis in Candida albicans is mediated by Cdr1-p extrusion and depletion of intracellular glutathione.Azole resistance by loss of function of the sterol Δ⁵,⁶-desaturase gene (ERG3) in Candida albicans does not necessarily decrease virulencePivotal role for a tail subunit of the RNA polymerase II mediator complex CgMed2 in azole tolerance and adherence in Candida glabrataAnalysis of natural variants of the human immunodeficiency virus type 1 gag-pol frameshift stem-loop structureCloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene.Roles of cellular respiration, CgCDR1, and CgCDR2 in Candida glabrata resistance to histatin 5.Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences.A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicansLoss of mitochondrial functions associated with azole resistance in Candida glabrata results in enhanced virulence in miceFungicidal synergism of fluconazole and cyclosporine in Candida albicans is not dependent on multidrug efflux transporters encoded by the CDR1, CDR2, CaMDR1, and FLU1 genes.
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Dominique Sanglard
@ast
Dominique Sanglard
@en
Dominique Sanglard
@es
Dominique Sanglard
@nl
Dominique Sanglard
@sl
type
label
Dominique Sanglard
@ast
Dominique Sanglard
@en
Dominique Sanglard
@es
Dominique Sanglard
@nl
Dominique Sanglard
@sl
prefLabel
Dominique Sanglard
@ast
Dominique Sanglard
@en
Dominique Sanglard
@es
Dominique Sanglard
@nl
Dominique Sanglard
@sl
P1053
K-6032-2017
P106
P1153
7005396991
P2038
Dominique_Sanglard
P2798
P31
P3829
P496
0000-0002-5244-4178
P569
2000-01-01T00:00:00Z