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Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancerVitamin D and the Epithelial to Mesenchymal TransitionSynthesis, structure, and biological activity of des-side chain analogues of 1α,25-dihydroxyvitamin D3 with substituents at C18TWIST1 is expressed in colorectal carcinomas and predicts patient survivalVitamin D and cancer: an update of in vitro and in vivo data.Novel snail1 target proteins in human colon cancer identified by proteomic analysis.Vitamin D receptor deficiency enhances Wnt/β-catenin signaling and tumor burden in colon cancer.Site-dependent E-cadherin cleavage and nuclear translocation in a metastatic colorectal cancer model.Exosomes enriched in stemness/metastatic-related mRNAS promote oncogenic potential in breast cancer.Vitamin D3 and colorectal cancer.Vitamin D Is a Multilevel Repressor of Wnt/b-Catenin Signaling in Cancer Cells.Interaction of vitamin D with membrane-based signaling pathwaysSNAI1 expression in colon cancer related with CDH1 and VDR downregulation in normal adjacent tissue.Twist1-induced activation of human fibroblasts promotes matrix stiffness by upregulating palladin and collagen α1(VI).The endocrine vitamin D system in the gut.Synthesis and biological evaluation of 1α,25-dihydroxyvitamin D₃ analogues with a long side chain at C12 and short C17 side chains.Vitamin D has wide regulatory effects on histone demethylase genes.KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells.Proteomic analysis of 1α,25-dihydroxyvitamin D3 action on human colon cancer cells reveals a link to splicing regulation.SPROUTY-2 and E-cadherin regulate reciprocally and dictate colon cancer cell tumourigenicity.The effects of 1,25-dihydroxyvitamin D3 on colon cancer cells depend on RhoA-ROCK-p38MAPK-MSK signaling.The transcription factors Snail1 and Snail2 repress vitamin D receptor during colon cancer progression.E-cadherin controls beta-catenin and NF-kappaB transcriptional activity in mesenchymal gene expression.The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells.The inhibition of Wnt/beta-catenin signalling by 1alpha,25-dihydroxyvitamin D3 is abrogated by Snail1 in human colon cancer cells.Snail1 transcriptional repressor binds to its own promoter and controls its expression.The first locked side-chain analogues of calcitriol (1alpha,25-dihydroxyvitamin D3) induce vitamin D receptor transcriptional activity.Vitamin D receptor expression and associated gene signature in tumour stromal fibroblasts predict clinical outcome in colorectal cancer.RhoA-ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells.Vitamin D: Proteases, protease inhibitors and cancer.The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer.The human PKP2/plakophilin-2 gene is induced by Wnt/β-catenin in normal and colon cancer-associated fibroblasts.Endothelial cell activation on 3D-matrices derived from PDGF-BB-stimulated fibroblasts is mediated by Snail1Calcitriol, the Bioactive Metabolite of Vitamin D, Increases Ventricular K Currents in Isolated Mouse CardiomyocytesDifferential distribution and enrichment of non-coding RNAs in exosomes from normal and Cancer-associated fibroblasts in colorectal cancerMechanisms of action of vitamin D in colon cancerVitamin D and Wnt3A have additive and partially overlapping modulatory effects on gene expression and phenotype in human colon fibroblasts.
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
María Jesús Larriba
@ast
María Jesús Larriba
@en
María Jesús Larriba
@es
María Jesús Larriba
@nl
María Jesús Larriba
@sl
type
label
María Jesús Larriba
@ast
María Jesús Larriba
@en
María Jesús Larriba
@es
María Jesús Larriba
@nl
María Jesús Larriba
@sl
prefLabel
María Jesús Larriba
@ast
María Jesús Larriba
@en
María Jesús Larriba
@es
María Jesús Larriba
@nl
María Jesús Larriba
@sl
P1053
O-4652-2014
P106
P1153
6505980554
P21
P31
P3829
P496
0000-0001-9035-7414