Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity.

Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity.

Item
http://www.wikidata.org/entity/Q40146386
Stem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injuryModel-based contextualization of in vitro toxicity data quantitatively predicts in vivo drug response in patients.In Vitro Model for Hepatotoxicity Studies Based on Primary Human Hepatocyte Cultivation in a Perfused 3D Bioreactor System.A Comparative Analysis of Drug-Induced Hepatotoxicity in Clinically Relevant Situations.High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities.Unraveling cellular pathways contributing to drug-induced liver injury by dynamical modeling.Evaluation of a human in vitro hepatocyte-NPC co-culture model for the prediction of idiosyncratic drug-induced liver injury: A pilot study.Characterization of Drug-Specific Signaling Between Primary Human Hepatocytes and Immune Cells.Hepatoprotective Effect of Carboxymethyl Pachyman in Fluorouracil-Treated CT26-Bearing Mice.Model-based identification of TNFα-induced IKKβ-mediated and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury compounds.Tanshinol ameliorates CCl4-induced liver fibrosis in rats through the regulation of Nrf2/HO-1 and NF-κB/IκBα signaling pathway.
P2860

Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity.

Item
http://www.wikidata.org/entity/Q40146386
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Activation of the Nrf2 respons ...... ard TNFα-induced cytotoxicity.
@en
type
label
Activation of the Nrf2 respons ...... ard TNFα-induced cytotoxicity.
@en
prefLabel
Activation of the Nrf2 respons ...... ard TNFα-induced cytotoxicity.
@en
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Activation of the Nrf2 respons ...... ard TNFα-induced cytotoxicity.
@en
P2093
P2860
P2888
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932