about
Targeting (cellular) lysosomal acid ceramidase by B13: design, synthesis and evaluation of novel DMG-B13 ester prodrugs.Cationic ceramides and analogues, LCL30 and LCL85, as adjuvants to photodynamic therapy of tumors.Synthesis, NMR characterization and divergent biological actions of 2'-hydroxy-ceramide/dihydroceramide stereoisomers in MCF7 cells.Synthesis and bioevaluation of omega-N-amino analogs of B13.Lysosomotropic acid ceramidase inhibitor induces apoptosis in prostate cancer cells.Regulation of the sphingosine-recycling pathway for ceramide generation by oxidative stress, and its role in controlling c-Myc/Max function.Comprehensive quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry.Structural requirements of ceramide and sphingosine based inhibitors of mitochondrial ceramidase.Inhibition of growth and telomerase activity by novel cationic ceramide analogs with high solubility in human head and neck squamous cell carcinoma cells.Radiolabeling of the sphingolipid backboneSimultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometryReceptor-interacting Ser/Thr kinase 1 (RIPK1) and myosin IIA-dependent ceramidosomes form membrane pores that mediate blebbing and necroptosis
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description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Zdzislaw M Szulc
@ast
Zdzislaw M Szulc
@en
Zdzislaw M Szulc
@es
Zdzislaw M Szulc
@nl
Zdzislaw M Szulc
@sl
type
label
Zdzislaw M Szulc
@ast
Zdzislaw M Szulc
@en
Zdzislaw M Szulc
@es
Zdzislaw M Szulc
@nl
Zdzislaw M Szulc
@sl
prefLabel
Zdzislaw M Szulc
@ast
Zdzislaw M Szulc
@en
Zdzislaw M Szulc
@es
Zdzislaw M Szulc
@nl
Zdzislaw M Szulc
@sl
P106
P21
P31
P496
0000-0003-1756-9028