Camptothecin enhances the frequency of oligonucleotide-directed gene repair in mammalian cells by inducing DNA damage and activating homologous recombination.
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Genetic spell-checking: gene editing using single-stranded DNA oligonucleotidesThe position of DNA cleavage by TALENs and cell synchronization influences the frequency of gene editing directed by single-stranded oligonucleotidesDifferential involvement of phosphatidylinositol 3-kinase-related protein kinases in hyperphosphorylation of replication protein A2 in response to replication-mediated DNA double-strand breaks.Reduction of gene repair by selenomethionine with the use of single-stranded oligonucleotides.Manipulation of cell cycle progression can counteract the apparent loss of correction frequency following oligonucleotide-directed gene repair.Simultaneous targeted exchange of two nucleotides by single-stranded oligonucleotides clusters within a region of about fourteen nucleotides.A comparison of synthetic oligodeoxynucleotides, DNA fragments and AAV-1 for targeted episomal and chromosomal gene repairA 'Semi-Protected Oligonucleotide Recombination' Assay for DNA Mismatch Repair in vivo Suggests Different Modes of Repair for Lagging Strand Mismatches.Increased efficiency of oligonucleotide-mediated gene repair through slowing replication fork progression.Xylazine as a drug of abuse and its effects on the generation of reactive species and DNA damage on human umbilical vein endothelial cells.Regulation of Gene Editing Activity Directed by Single-Stranded Oligonucleotides and CRISPR/Cas9 Systems.Y-box binding protein 1 enhances DNA topoisomerase 1 activity and sensitivity to camptothecin via direct interaction.Stimulation of oligonucleotide-directed gene correction by Redβ expression and MSH2 depletion in human HT1080 cellsThe involvement of replication in single stranded oligonucleotide-mediated gene repair.Gene therapy progress and prospects: targeted gene repair.Insertional Mutagenesis by CRISPR/Cas9 Ribonucleoprotein Gene Editing in Cells Targeted for Point Mutation Repair Directed by Short Single-Stranded DNA Oligonucleotides.Progress and prospects: oligonucleotide-directed gene modification in mouse embryonic stem cells: a route to therapeutic application.Emerging gene editing strategies for Duchenne muscular dystrophy targeting stem cells.Generation of a mouse mutant by oligonucleotide-mediated gene modification in ES cells.Enhanced gene repair mediated by methyl-CpG-modified single-stranded oligonucleotidesAPE1 overexpression promotes the progression of ovarian cancer and serves as a potential therapeutic target.The combination of hyperthermia or chemotherapy with gimeracil for effective radiosensitization.Parameters of oligonucleotide-mediated gene modification in mouse ES cellsDNA breakage associated with targeted gene alteration directed by DNA oligonucleotides.Multiple roles for MSH2 in the repair of a deletion mutation directed by modified single-stranded oligonucleotides.Recovery of cell cycle delay following targeted gene repair by oligonucleotides.Site-specific base changes in the coding or promoter region of the human beta- and gamma-globin genes by single-stranded oligonucleotides.Oligonucleotide delivery by nucleofection does not rescue the reduced proliferation phenotype of gene-edited cellsCombinatorial gene editing in mammalian cells using ssODNs and TALENs.Strand bias influences the mechanism of gene editing directed by single-stranded DNA oligonucleotides.Differential contribution of the Fanconi anemia-related proteins to repair of several types of DNA damage in cultured silkworm cells.DNA damage response pathway and replication fork stress during oligonucleotide directed gene editing.A Standard Methodology to Examine On-site Mutagenicity As a Function of Point Mutation Repair Catalyzed by CRISPR/Cas9 and SsODN in Human CellsDeletion of MAG1 and MRE11 enhances the sensitivity of the Saccharomyces cerevisiae HUG1P-GFP promoter-reporter construct to genotoxicity.Implications of cell cycle progression on functional sequence correction by short single-stranded DNA oligonucleotides.Mechanisms of precise genome editing using oligonucleotide donors.Gene homozygosis and mitotic recombination induced by camptothecin and irinotecan in Aspergillus nidulans diploid cells.
P2860
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P2860
Camptothecin enhances the frequency of oligonucleotide-directed gene repair in mammalian cells by inducing DNA damage and activating homologous recombination.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Camptothecin enhances the freq ...... ting homologous recombination.
@en
type
label
Camptothecin enhances the freq ...... ting homologous recombination.
@en
prefLabel
Camptothecin enhances the freq ...... ting homologous recombination.
@en
P2860
P356
P1476
Camptothecin enhances the freq ...... ting homologous recombination.
@en
P2093
Eric B Kmiec
Luciana Ferrara
P2860
P304
P356
10.1093/NAR/GKH822
P577
2004-10-05T00:00:00Z