ROS mediate the hypoxic repression of the hepcidin gene by inhibiting C/EBPalpha and STAT-3.
about
Regulation of cellular iron metabolismIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesEvidence for a lack of a direct transcriptional suppression of the iron regulatory peptide hepcidin by hypoxia-inducible factorsRegulation of resistin by cyclic mechanical stretch in cultured rat vascular smooth muscle cellsCholestasis downregulate hepcidin expression through inhibiting IL-6-induced phosphorylation of signal transducer and activator of transcription 3 signalingFuture alternative therapies for β-thalassemia.Hepcidin and the iron enigma in HCV infection.Successful antiviral therapy is associated with a decrease of serum prohepcidin in chronic hepatitis C.Hypoxia induces chemoresistance in ovarian cancer cells by activation of signal transducer and activator of transcription 3.Molecular mechanisms of hepcidin regulation: implications for the anemia of CKD.Hepcidin in beta-thalassemia.Morphological and flow-cytometric analysis of haemin-induced human neutrophil activation: implications for transfusion-related acute lung injuryIron regulator hepcidin exhibits antiviral activity against hepatitis C virus.Iron metabolism in thalassemia and sickle cell diseaseHypoxia-inducible factor-1alpha enhances haptoglobin gene expression by improving binding of STAT3 to the promoter.Hepcidin: A Critical Regulator of Iron Metabolism during HypoxiaIron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat model.Severe microcytic anemia but increased erythropoiesis in mice lacking Hfe or Tfr2 and Tmprss6Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietin-mediated increase in erythropoiesisHepcidin levels in children with chronic liver disease.Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPalphaHepcidin modulation in human diseases: from research to clinic.Hepcidin and Iron Metabolism in Pregnancy: Correlation with Smoking and Birth Weight and Length.Synthetic and natural iron chelators: therapeutic potential and clinical useIron homeostasis in the liver.Systematic discovery and characterization of regulatory motifs in ENCODE TF binding experiments.Iron-deficiency anemia secondary to mutations in genes controlling hepcidin.Iron metabolism in Nonalcoholic Fatty Liver Disease.Iron and oxygen sensing: a tale of 2 interacting elements?A complex signaling network involving protein kinase CK2 is required for hepatitis C virus core protein-mediated modulation of the iron-regulatory hepcidin gene expression.Basal expression of copper transporter 1 in intestinal epithelial cells is regulated by hypoxia-inducible factor 2α.Hypoxia inhibits hepcidin expression in HuH7 hepatoma cells via decreased SMAD4 signaling.Deferasirox reduces oxidative stress in patients with transfusion dependency.Function of the hemochromatosis protein HFE: Lessons from animal models.Differences in activation of mouse hepcidin by dietary iron and parenterally administered iron dextran: compartmentalization is critical for iron sensing.Serum prohepcidin reflects the degree of liver function impairment in liver cirrhosis.Erythroid but not cytogenetic response in a case with 5q- syndrome: a delayed effect of lenalidomide or a consequence of deferasirox treatment?Does Hypoxia Cause Carcinogenic Iron Accumulation in Alcoholic Liver Disease (ALD)?Strain- and time-dependent alterations in hepatic iron metabolism in a murine model of nonalcoholic steatohepatitis.Pathophysiology and treatment of patients with beta-thalassemia - an update.
P2860
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P2860
ROS mediate the hypoxic repression of the hepcidin gene by inhibiting C/EBPalpha and STAT-3.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
ROS mediate the hypoxic repres ...... ibiting C/EBPalpha and STAT-3.
@en
type
label
ROS mediate the hypoxic repres ...... ibiting C/EBPalpha and STAT-3.
@en
prefLabel
ROS mediate the hypoxic repres ...... ibiting C/EBPalpha and STAT-3.
@en
P2093
P1476
ROS mediate the hypoxic repres ...... ibiting C/EBPalpha and STAT-3.
@en
P2093
Hye-Lim Kim
Jong-Wan Park
Si-On Choi
Young-Suk Cho
P304
P356
10.1016/J.BBRC.2007.02.137
P577
2007-03-05T00:00:00Z