Gastrin-releasing peptide activates Akt through the epidermal growth factor receptor pathway and abrogates the effect of gefitinib.
about
International Union of Pharmacology. LXVIII. Mammalian bombesin receptors: nomenclature, distribution, pharmacology, signaling, and functions in normal and disease statesBombesin-related peptides and their receptors: recent advances in their role in physiology and disease statesInsights into bombesin receptors and ligands: Highlighting recent advancesLaser capture microdissection and protein microarray analysis of human non-small cell lung cancer: differential epidermal growth factor receptor (EGPR) phosphorylation events associated with mutated EGFR compared with wild typeBombesin receptor subtype 3 as a potential target for obesity and diabetes.Tumor antigen-targeted, monoclonal antibody-based immunotherapy: clinical response, cellular immunity, and immunoescape.HGF-independent potentiation of EGFR action by c-MetBombesin receptor subtype-3 agonists stimulate the growth of lung cancer cells and increase EGF receptor tyrosine phosphorylation.Autocrine production of amphiregulin predicts sensitivity to both gefitinib and cetuximab in EGFR wild-type cancers.Gastrin-releasing peptide receptor expression in non-cancerous bronchial epithelia is associated with lung cancer: a case-control study.Combination of gastrin-releasing peptide antagonist with cytotoxic agents produces synergistic inhibition of growth of human experimental colon cancersGastrin-releasing peptide receptors in the central nervous system: role in brain function and as a drug target.Elevated gastrin-releasing peptide receptor mRNA expression in buccal mucosa: association with head and neck squamous cell carcinoma.Gastrointestinal hormones stimulate growth of Foregut Neuroendocrine Tumors by transactivating the EGF receptor.Gastrointestinal growth factors and hormones have divergent effects on Akt activation.Constructing bioactive peptides with pH-dependent activities.Neuromedin B receptors regulate EGF receptor tyrosine phosphorylation in lung cancer cells.BDNF/TrkB content and interaction with gastrin-releasing peptide receptor blockade in colorectal cancer.How gastrin-releasing peptide receptor (GRPR) and αvβ3 integrin expression reflect reorganization features of tumors after hyperthermia treatments.Significance of gastrin-releasing peptide in ovarian cancer ES2 cellsUncovering potential downstream targets of oncogenic GRPR overexpression in prostate carcinomas harboring ETS rearrangements.Neuropeptide gastrin-releasing peptide induces PI3K/reactive oxygen species-dependent migration in lung adenocarcinoma cells.Correlation of the Ga-68-bombesin analog Ga-68-BZH3 with receptors expression in gliomas as measured by quantitative dynamic positron emission tomography (dPET) and gene arrays.A possible new target in lung-cancer cells: The orphan receptor, bombesin receptor subtype-3.Epigallocatechin gallate protects BEAS-2B cells from lipopolysaccharide-induced apoptosis through upregulation of gastrin-releasing peptide.
P2860
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P2860
Gastrin-releasing peptide activates Akt through the epidermal growth factor receptor pathway and abrogates the effect of gefitinib.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Gastrin-releasing peptide acti ...... gates the effect of gefitinib.
@en
type
label
Gastrin-releasing peptide acti ...... gates the effect of gefitinib.
@en
prefLabel
Gastrin-releasing peptide acti ...... gates the effect of gefitinib.
@en
P2093
P1476
Gastrin-releasing peptide acti ...... gates the effect of gefitinib.
@en
P2093
Autumn Gaither-Davis
Diane L Carlisle
Jill M Siegfried
Michelle C Swick
P304
P356
10.1016/J.YEXCR.2007.01.016
P407
P577
2007-02-03T00:00:00Z