Epitope-dependent avidity thresholds for cytotoxic T-lymphocyte clearance of virus-infected cells.
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High avidity CD8+ T cells efficiently eliminate motile HIV-infected targets and execute a locally focused program of anti-viral functionEvidence for Protection against Chronic Hepatitis C Virus Infection in Chimpanzees by Immunization with Replicating Recombinant Vaccinia VirusSang Froid in a time of trouble: is a vaccine against HIV possible?Candidate vaccine sequences to represent intra- and inter-clade HIV-1 variation.Effective simian immunodeficiency virus-specific CD8+ T cells lack an easily detectable, shared characteristic.Generation of robust CD8+ T-cell responses against subdominant epitopes in conserved regions of HIV-1 by repertoire mining with mimotopes.Dynamic regulation of functionally distinct virus-specific T cells.Dynamics of viral evolution and CTL responses in HIV-1 infectionT-cell correlates of vaccine efficacy after a heterologous simian immunodeficiency virus challenge.Immunodominant HIV-1-specific HLA-B- and HLA-C-restricted CD8+ T cells do not differ in polyfunctionality.Pathogenesis and treatment of HIV infection: the cellular, the immune system and the neuroendocrine systems perspective.Escape is a more common mechanism than avidity reduction for evasion of CD8+ T cell responses in primary human immunodeficiency virus type 1 infection.Identification and visualization of CD8+ T cell mediated IFN-γ signaling in target cells during an antiviral immune response in the brain.High-functional-avidity cytotoxic T lymphocyte responses to HLA-B-restricted Gag-derived epitopes associated with relative HIV controlHigh-avidity, high-IFNγ-producing CD8 T-cell responses following immune selection during HIV-1 infection.Epitope targeting and viral inoculum are determinants of Nef-mediated immune evasion of HIV-1 from cytotoxic T lymphocytesExpansion of polyfunctional HIV-specific T cells upon stimulation with mRNA electroporated dendritic cells in the presence of immunomodulatory drugsEvolution of human immunodeficiency virus type 1 cytotoxic T-lymphocyte epitopes: fitness-balanced escape.Recognition of escape variants in ELISPOT does not always predict CD8+ T-cell recognition of simian immunodeficiency virus-infected cells expressing the same variant sequences.Magnitude, breadth, and functional profile of T-cell responses during human immunodeficiency virus primary infection with B and BF viral variants.TCR clonotypes modulate the protective effect of HLA class I molecules in HIV-1 infectionEarly antigen presentation of protective HIV-1 KF11Gag and KK10Gag epitopes from incoming viral particles facilitates rapid recognition of infected cells by specific CD8+ T cellsCross-reactivity of T cells and its role in the immune systemDifferential antigen presentation kinetics of CD8+ T-cell epitopes derived from the same viral protein.Nonhuman primate models and the failure of the Merck HIV-1 vaccine in humans.Toward an AIDS vaccine.Packaging limits and stability of HIV-1 sequences in a coxsackievirus B vector.CTL quality and the control of human retroviral infections.Immune Signature of Enhanced Functional Avidity CD8+ T Cells in vivo Induced by Vaccinia Vectored Vaccine.T cell sensitivity and the outcome of viral infection.T cells induced by recombinant chimpanzee adenovirus alone and in prime-boost regimens decrease chimeric EcoHIV/NDK challenge virus loadFunctional avidity: a measure to predict the efficacy of effector T cells?Enhanced cytotoxicity and decreased CD8 dependence of human cancer-specific cytotoxic T lymphocytes after vaccination with low peptide dose.T-Cell Receptor (TCR) Clonotype-Specific Differences in Inhibitory Activity of HIV-1 Cytotoxic T-Cell Clones Is Not Mediated by TCR Alone.HIV-1-Specific Chimeric Antigen Receptors Based on Broadly Neutralizing Antibodies.Antiviral activity of human immunodeficiency virus type 1 Gag-specific cytotoxic T lymphocyte targeting is not necessarily intrinsically superior to envelope targetingHIV-1 epitopes presented by MHC class I types associated with superior immune containment of viremia have highly constrained fitness landscapes.Retracing our STEP towards a successful CTL-based HIV-1 vaccine.Fine-tuning of T-cell receptor avidity to increase HIV epitope variant recognition by cytotoxic T lymphocytes.Simian immunodeficiency virus-specific CD8+ T cells recognize Vpr- and Rev-derived epitopes early after infection
P2860
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P2860
Epitope-dependent avidity thresholds for cytotoxic T-lymphocyte clearance of virus-infected cells.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Epitope-dependent avidity thre ...... rance of virus-infected cells.
@en
type
label
Epitope-dependent avidity thre ...... rance of virus-infected cells.
@en
prefLabel
Epitope-dependent avidity thre ...... rance of virus-infected cells.
@en
P2093
P2860
P356
P1433
P1476
Epitope-dependent avidity thre ...... rance of virus-infected cells.
@en
P2093
Michael S Bennett
Mirabelle Dagarag
Otto O Yang
P2860
P304
P356
10.1128/JVI.02362-06
P407
P577
2007-02-28T00:00:00Z