Mechanical loading down-regulates peroxisome proliferator-activated receptor gamma in bone marrow stromal cells and favors osteoblastogenesis at the expense of adipogenesis.
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Mechanical loading, damping, and load-driven bone formation in mouse tibiaeControl of stem cell fate by physical interactions with the extracellular matrixExercise Regulation of Marrow Adipose TissueIn situ spatiotemporal mapping of flow fields around seeded stem cells at the subcellular length scalePhysiological mechanisms and therapeutic potential of bone mechanosensing.Environmental physical cues determine the lineage specification of mesenchymal stem cellsKif3a deficiency reverses the skeletal abnormalities in Pkd1 deficient mice by restoring the balance between osteogenesis and adipogenesisTreadmill training regulates β-catenin signaling through phosphorylation of GSK-3β in lumbar vertebrae of ovariectomized ratsMechanical signals as anabolic agents in bone.Low-level vibrations retain bone marrow's osteogenic potential and augment recovery of trabecular bone during reambulationAdipogenesis is inhibited by brief, daily exposure to high-frequency, extremely low-magnitude mechanical signalsMesenchymal stem cell mechanobiology and emerging experimental platforms.Primary cilia-mediated mechanotransduction in human mesenchymal stem cells.Mechanical strain modulates age-related changes in the proliferation and differentiation of mouse adipose-derived stromal cells.Conditional disruption of Pkd1 in osteoblasts results in osteopenia due to direct impairment of bone formation.Bone metabolism in obesity and weight loss.Bone marrow fat accumulation accelerated by high fat diet is suppressed by exercise.A Memory of Early Life Physical Activity Is Retained in Bone Marrow of Male Rats Fed a High-Fat Diet.Rates of bone loss in young adult males.Bone acquisition in healthy young females is reciprocally related to marrow adiposity.Mechanical Signals As a Non-Invasive Means to Influence Mesenchymal Stem Cell Fate, Promoting Bone and Suppressing the Fat PhenotypeObesity-mediated inflammatory microenvironment stimulates osteoclastogenesis and bone loss in mice.Mapping the mechanome of live stem cells using a novel method to measure local strain fields in situ at the fluid-cell interfaceExercise Regulation of Marrow Fat in the Setting of PPARγ Agonist Treatment in Female C57BL/6 Mice.Mechanical strain downregulates C/EBPβ in MSC and decreases endoplasmic reticulum stress.Mechanical signal influence on mesenchymal stem cell fate is enhanced by incorporation of refractory periods into the loading regimen.Biomechanical forces in the skeleton and their relevance to bone metastasis: biology and engineering considerations.Mechanical modulation of osteochondroprogenitor cell fate.Low dietary calcium and obesity: a comparative study in genetically obese and normal rats during early growth.Epigenetic changes during mechanically induced osteogenic lineage commitment.Antiosteoporotic Activity of Dioscorea alata L. cv. Phyto through Driving Mesenchymal Stem Cells Differentiation for Bone FormationEffects of obesity on bone metabolism.Shear stress induced by an interstitial level of slow flow increases the osteogenic differentiation of mesenchymal stem cells through TAZ activationMechanical regulation of glycogen synthase kinase 3β (GSK3β) in mesenchymal stem cells is dependent on Akt protein serine 473 phosphorylation via mTORC2 protein.Short-term physical activity intervention decreases femoral bone marrow adipose tissue in young children: a pilot study.Regional fat depots and their relationship to bone density and microarchitecture in young oligo-amenorrheic athletes.Dynamic Fluid Flow Mechanical Stimulation Modulates Bone Marrow Mesenchymal Stem CellsComparison of Effects of Mechanical Stretching on Osteogenic Potential of ASCs and BMSCs.Physical Activity Increases the Total Number of Bone-Marrow-Derived Mesenchymal Stem Cells, Enhances Their Osteogenic Potential, and Inhibits Their Adipogenic PropertiesMechanical regulation of signaling pathways in bone.
P2860
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P2860
Mechanical loading down-regulates peroxisome proliferator-activated receptor gamma in bone marrow stromal cells and favors osteoblastogenesis at the expense of adipogenesis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Mechanical loading down-regula ...... t the expense of adipogenesis.
@en
type
label
Mechanical loading down-regula ...... t the expense of adipogenesis.
@en
prefLabel
Mechanical loading down-regula ...... t the expense of adipogenesis.
@en
P2093
P356
P1433
P1476
Mechanical loading down-regula ...... t the expense of adipogenesis.
@en
P2093
Alain Guignandon
Aline Martin
David B Jones
Laurence Vico
Luc Malaval
Marie-Hélène Lafage-Proust
Sylvie Peyroche
Valentin David
P304
P356
10.1210/EN.2006-1704
P407
P577
2007-02-22T00:00:00Z