TAK1 MAPK kinase kinase mediates transforming growth factor-beta signaling by targeting SnoN oncoprotein for degradation.
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Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promotersThe Caenorhabditis elegans JNK signaling pathway activates expression of stress response genes by derepressing the Fos/HDAC repressor complexIntestinal epithelial-derived TAK1 signaling is essential for cytoprotection against chemical-induced colitisInhibition of transforming growth factor-activated kinase 1 (TAK1) blocks and reverses epithelial to mesenchymal transition of mesothelial cellsProtein phosphatase 2A is a negative regulator of transforming growth factor-beta1-induced TAK1 activation in mesangial cellsArsenic trioxide induces a beclin-1-independent autophagic pathway via modulation of SnoN/SkiL expression in ovarian carcinoma cells.Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitisSnoN in mammalian development, function and diseases.Multiple transcription factor families regulate axon growth and regenerationTGF-β1 induced transdifferentiation of rpe cells is mediated by TAK1.TGF-β-activated kinase-1: New insights into the mechanism of TGF-β signaling and kidney disease.TAK1-binding protein 1, TAB1, mediates osmotic stress-induced TAK1 activation but is dispensable for TAK1-mediated cytokine signalingGeneration of a conditional mutant allele for Tab1 in mouseTAK1 regulates hepatic lipid homeostasis through SREBPSki and SnoN, potent negative regulators of TGF-beta signaling.Transforming growth factor-beta (TGF-beta1) activates TAK1 via TAB1-mediated autophosphorylation, independent of TGF-beta receptor kinase activity in mesangial cells.TAK1 kinase determines TRAIL sensitivity by modulating reactive oxygen species and cIAP.The TGFβ1 pathway is required for NFκB dependent gene expression in mouse keratinocytes.TAK1, more than just innate immunity.TAK1 is a key modulator of the profibrogenic phenotype of human ileal myofibroblasts in Crohn's disease.The critical role of TAK1 in accentuated epithelial to mesenchymal transition in obliterative bronchiolitis after lung transplantation.Aerobic glycolysis suppresses p53 activity to provide selective protection from apoptosis upon loss of growth signals or inhibition of BCR-Abl.Spatial aspects in the SMAD signaling pathway.TAK1
P2860
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P2860
TAK1 MAPK kinase kinase mediates transforming growth factor-beta signaling by targeting SnoN oncoprotein for degradation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
TAK1 MAPK kinase kinase mediat ...... N oncoprotein for degradation.
@en
type
label
TAK1 MAPK kinase kinase mediat ...... N oncoprotein for degradation.
@en
prefLabel
TAK1 MAPK kinase kinase mediat ...... N oncoprotein for degradation.
@en
P2093
P2860
P356
P1476
TAK1 MAPK kinase kinase mediat ...... N oncoprotein for degradation.
@en
P2093
Emily Omori
Kunihiro Matsumoto
Shunsuke Ishii
Taisuke Kajino
P2860
P304
P356
10.1074/JBC.M700875200
P407
P577
2007-02-02T00:00:00Z