Cyclophosphamide enhances the antitumor efficacy of adoptively transferred immune cells through the induction of cytokine expression, B-cell and T-cell homeostatic proliferation, and specific tumor infiltration.
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Oncolytic viruses as therapeutic cancer vaccinesCancer immunotherapy via combining oncolytic virotherapy with chemotherapy: recent advancesTumor infiltrating lymphocytes in ovarian cancerCyclophosphamide induces bone marrow to yield higher numbers of precursor dendritic cells in vitro capable of functional antigen presentation to T cells in vivo.Cyclophosphamide enhances immunity by modulating the balance of dendritic cell subsets in lymphoid organs.Redirecting the immune response: role of adoptive T cell therapy.Immunomodulatory effects of cyclophosphamide and implementations for vaccine design.Cyclophosphamide induces dynamic alterations in the host microenvironments resulting in a Flt3 ligand-dependent expansion of dendritic cells.Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C)Dendritic cell recovery post-lymphodepletion: a potential mechanism for anti-cancer adoptive T cell therapy and vaccinationIntratumoral temozolomide synergizes with immunotherapy in a T cell-dependent fashion.Treatment of multiple myeloma with adoptively transferred chimeric NKG2D receptor-expressing T cellsPlatinum-based drugs disrupt STAT6-mediated suppression of immune responses against cancer in humans and miceSynergy of brief activation of CD8 T-cells in the presence of IL-12 and adoptive transfer into lymphopenic hosts promotes tumor clearance and anti-tumor memory.Both exogenous commensal and endogenous self antigens stimulate T cell proliferation under lymphopenic conditionsImmune microenvironments in solid tumors: new targets for therapy.Metronomic cyclophosphamide eradicates large implanted GL261 gliomas by activating antitumor Cd8(+) T-cell responses and immune memoryTreatment with targeted vesicular stomatitis virus generates therapeutic multifunctional anti-tumor memory CD4 T cells.Pharmacological Inhibition of β3 Integrin Reduces the Inflammatory Toxicities Caused by Oncolytic Adenovirus without Compromising Anticancer Activity.Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning.Circulating IL-15 exists as heterodimeric complex with soluble IL-15Rα in human and mouse serum.Polyfunctional CD4⁺ T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy.Adoptive transfer of cytotoxic T lymphocytes targeting two different antigens limits antigen loss and tumor escapeInduction of tumoricidal function in CD4+ T cells is associated with concomitant memory and terminally differentiated phenotypeNonalloreactive T cells prevent donor lymphocyte infusion-induced graft-versus-host disease by controlling microbial stimuli.CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.The Italian Network for Tumor Biotherapy (NIBIT): getting together to push the field forward.Low-dose cyclophosphamide administered as daily or single dose enhances the antitumor effects of a therapeutic HPV vaccine.Antigen spreading-induced CD8+T cells confer protection against the lethal challenge of wild-type malignant mesothelioma by eliminating myeloid-derived suppressor cells.T-cell activation by treatment of cancer patients with EMD 521873 (Selectikine), an IL-2/anti-DNA fusion protein.Effector CD8+ T-cell Engraftment and Antitumor Immunity in Lymphodepleted Hosts Is IL7Rα Dependent.Ubiquitin-like Molecule ISG15 Acts as an Immune Adjuvant to Enhance Antigen-specific CD8 T-cell Tumor Immunity.Transforming growth factor-beta receptor blockade augments the effectiveness of adoptive T-cell therapy of established solid cancers.Glioma stem cells and immunotherapy for the treatment of malignant gliomas.Inflammatory Signals Regulate IL-15 in Response to Lymphodepletion.Negative regulators in homeostasis of naïve peripheral T cells.Safety and efficacy of a genetic vaccine targeting telomerase plus chemotherapy for the therapy of canine B-cell lymphomaRadiofrequency thermal ablation of breast tumors combined with intralesional administration of IL-7 and IL-15 augments anti-tumor immune responses and inhibits tumor development and metastasis.Immunotherapy for liver tumors: present status and future prospects.Oncolytic virotherapy as a personalized cancer vaccine.
P2860
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P2860
Cyclophosphamide enhances the antitumor efficacy of adoptively transferred immune cells through the induction of cytokine expression, B-cell and T-cell homeostatic proliferation, and specific tumor infiltration.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Cyclophosphamide enhances the ...... d specific tumor infiltration.
@en
type
label
Cyclophosphamide enhances the ...... d specific tumor infiltration.
@en
prefLabel
Cyclophosphamide enhances the ...... d specific tumor infiltration.
@en
P2093
P1476
Cyclophosphamide enhances the ...... d specific tumor infiltration.
@en
P2093
Carlo Ramoni
Enrico Proietti
Federica Moschella
Filippo Belardelli
Irene Canini
Laura Bracci
Mara Valentini
Paola Sestili
Sara Baccarini
Sonia Maccari
P304
P356
10.1158/1078-0432.CCR-06-1209
P407
P433
P577
2007-01-01T00:00:00Z