Sphingosine-induced apoptosis in rhabdomyosarcoma cell lines is dependent on pre-mitochondrial Bax activation and post-mitochondrial caspases.
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Role of Calcium Signals on Hydrogen Peroxide-Induced Apoptosis in Human Myeloid HL-60 CellsMitochondrially targeted ceramides preferentially promote autophagy, retard cell growth, and induce apoptosis.Regulating survival and development in the retina: key roles for simple sphingolipids.SapC-DOPS nanovesicles induce Smac- and Bax-dependent apoptosis through mitochondrial activation in neuroblastomas.Insulin-like growth factor 1 receptor antibody induces rhabdomyosarcoma cell death via a process involving AKT and Bcl-x(L).Sphingolipids: regulators of crosstalk between apoptosis and autophagyCeramide and mitochondria in ischemia/reperfusion.Sphingolipids and expression regulation of genes in cancer.Sphingolipids and mitochondrial apoptosis.Sphingosine suppresses mesothelioma cell proliferation by inhibiting PKC-δ and inducing cell cycle arrest at the G(0)/G(1) phase.Sphingosine induces apoptosis in MKN-28 human gastric cancer cells in an SDK-dependent manner.Asymmetric synthesis and cytotoxic activity of isomeric phytosphingosine derivatives.Ceramide-induced G2 arrest in rhabdomyosarcoma (RMS) cells requires p21Cip1/Waf1 induction and is prevented by MDM2 overexpression.Cell death pathways as therapeutic targets in rhabdomyosarcoma.Caspase-3 mediated release of SAC domain containing fragment from Par-4 is necessary for the sphingosine-induced apoptosis in Jurkat cells.Aerobic training in rats increases skeletal muscle sphingomyelinase and serine palmitoyltransferase activity, while decreasing ceramidase activity.Proapoptotic Bax and Bak proteins form stable protein-permeable pores of tunable size.Bax siRNA promotes survival of cultured and allografted granule cell precursors through blockade of caspase-3 cleavage.Sphingosine Toxicity in EAE and MS: Evidence for Ceramide Generation via Serine-Palmitoyltransferase Activation.Sphingosine induces apoptosis in hippocampal neurons and astrocytes by activating caspase-3/-9 via a mitochondrial pathway linked to SDK/14-3-3 protein/Bax/cytochrome c.Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea.Protein phosphatase 1-dependent dephosphorylation of Akt is the prime signaling event in sphingosine-induced apoptosis in Jurkat cells.
P2860
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P2860
Sphingosine-induced apoptosis in rhabdomyosarcoma cell lines is dependent on pre-mitochondrial Bax activation and post-mitochondrial caspases.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Sphingosine-induced apoptosis ...... d post-mitochondrial caspases.
@en
type
label
Sphingosine-induced apoptosis ...... d post-mitochondrial caspases.
@en
prefLabel
Sphingosine-induced apoptosis ...... d post-mitochondrial caspases.
@en
P2093
P1433
P1476
Sphingosine-induced apoptosis ...... d post-mitochondrial caspases.
@en
P2093
Belinda T Doyle
Darren C Phillips
Janet A Houghton
Sophie Martin
P304
P356
10.1158/0008-5472.CAN-06-2374
P407
P577
2007-01-01T00:00:00Z