Mutations in calpain 3 associated with limb girdle muscular dystrophy: analysis by molecular modeling and by mutation in m-calpain.
about
Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpainsNovel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscleHomology modeling study of bovine μ-calpain inhibitor-binding domains.Calpain 3 is important for muscle regeneration: evidence from patients with limb girdle muscular dystrophies.Gene expression profiling of skeletal muscle of nursing pigletsActivation of m-calpain (calpain II) by epidermal growth factor is limited by protein kinase A phosphorylation of m-calpainAutolytic activation of calpain 3 proteinase is facilitated by calmodulin proteinPathogenity of some limb girdle muscular dystrophy mutations can result from reduced anchorage to myofibrils and altered stability of calpain 3.Loss of calpain-3 autocatalytic activity in LGMD2A patients with normal protein expression.CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation in a mouse modelThe calpains: modular designs and functional diversity.Screening of calpain-3 autolytic activity in LGMD muscle: a functional map of CAPN3 gene mutations.Calpain 3, the "gatekeeper" of proper sarcomere assembly, turnover and maintenance.Will you still need me (Ca2+ , TnT, and DHPR), will you still cleave me (calpain), when I'm 64?Structure-function relationships in calpains.Fetuin A stabilizes m-calpain and facilitates plasma membrane repair.Electrostatic interactions of domain III stabilize the inactive conformation of mu-calpain.Calpain activation by cooperative Ca2+ binding at two non-EF-hand sites.Insertion sequence 1 of muscle-specific calpain, p94, acts as an internal propeptide.Limb girdle muscular dystrophy in a sibling pair with a homozygous Ser606Leu mutation in the alternatively spliced IS2 region of calpain 3.Structures of human calpain-3 protease core with and without bound inhibitor reveal mechanisms of calpain activation.Autosomal dominant calpainopathy due to heterozygous CAPN3 c.643_663del21.
P2860
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P2860
Mutations in calpain 3 associated with limb girdle muscular dystrophy: analysis by molecular modeling and by mutation in m-calpain.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Mutations in calpain 3 associa ...... and by mutation in m-calpain.
@en
type
label
Mutations in calpain 3 associa ...... and by mutation in m-calpain.
@en
prefLabel
Mutations in calpain 3 associa ...... and by mutation in m-calpain.
@en
P2093
P2860
P1433
P1476
Mutations in calpain 3 associa ...... and by mutation in m-calpain.
@en
P2093
Beckmann JS
Moldoveanu T
Petrounevitch V
P2860
P304
P356
10.1016/S0006-3495(01)76229-7
P407
P577
2001-06-01T00:00:00Z