Live-cell imaging of enzyme-substrate interaction reveals spatial regulation of PTP1B.
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PTP1B regulates Eph receptor function and traffickingCellular biochemistry methods for investigating protein tyrosine phosphatasesSubcellular Partitioning of Protein Tyrosine Phosphatase 1B to the Endoplasmic Reticulum and Mitochondria Depends Sensitively on the Composition of Its Tail AnchorDynamic recruitment of protein tyrosine phosphatase PTPD1 to EGF stimulation sites potentiates EGFR activationSingle Particle Tracking Reveals that EGFR Signaling Activity Is Amplified in Clathrin-Coated PitsStructure of a tyrosine phosphatase adhesive interaction reveals a spacer-clamp mechanismThe protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules.Conformation-Sensing Antibodies Stabilize the Oxidized Form of PTP1B and Inhibit Its Phosphatase ActivityProtein tyrosine phosphatase, PTP1B, expression and activity in rat corneal endothelial cellsReversible cryo-arrest for imaging molecules in living cells at high spatial resolution.Dock/Nck facilitates PTP61F/PTP1B regulation of insulin signalling.Identification of tyrosine phosphatase ligands for contactin cell adhesion molecules.Diffusion is capable of translating anisotropic apoptosis initiation into a homogeneous execution of cell deathSignalling ballet in space and timeGenetically targetable and color-switching fluorescent probeReaction-diffusion systems in intracellular molecular transport and controlMicrofluidics-integrated time-lapse imaging for analysis of cellular dynamics.Ubiquitination switches EphA2 vesicular traffic from a continuous safeguard to a finite signalling mode.B cell activation triggered by the formation of the small receptor cluster: a computational study.Substrate specificity of protein tyrosine phosphatases 1B, RPTPα, SHP-1, and SHP-2.PTPIP51 in protein interactions: regulation and in situ interacting partners.Regulation of signaling at regions of cell-cell contact by endoplasmic reticulum-bound protein-tyrosine phosphatase 1B.Superoxide anion radicals induce IGF-1 resistance through concomitant activation of PTP1B and PTEN.Reporting from the field: genetically encoded fluorescent reporters uncover signaling dynamics in living biological systems.Signalling by protein phosphatases and drug development: a systems-centred view.Integrated experimental and model-based analysis reveals the spatial aspects of EGFR activation dynamics.Protein tyrosine phosphatases: regulatory mechanisms.Prediction of substrate-enzyme-product interaction based on molecular descriptors and physicochemical properties.Fluorescent protein-based biosensors: resolving spatiotemporal dynamics of signaling.Strategies for protein synthetic biology.Post-translational modification: nature's escape from genetic imprisonment and the basis for dynamic information encoding.Microspectroscopy reveals mechanisms of lymphocyte activation.Resonance energy transfer-based fluorescent probes for Hg2+, Cu2+ and Fe2+/Fe3+ ions.Subcellular functions of proteins under fluorescence single-cell microscopy.A fluorescence energy transfer-based mechanical stress sensor for specific proteins in situ.From dynamic self-assembly to networked chemical systems.EGF-dependent re-routing of vesicular recycling switches spontaneous phosphorylation suppression to EGFR signaling.Molecular tools for cell and systems biology.The autodepalmitoylating activity of APT maintains the spatial organization of palmitoylated membrane proteins.Covalent modification cycles through the spatial prism.
P2860
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P2860
Live-cell imaging of enzyme-substrate interaction reveals spatial regulation of PTP1B.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Live-cell imaging of enzyme-substrate interaction reveals spatial regulation of PTP1B.
@en
type
label
Live-cell imaging of enzyme-substrate interaction reveals spatial regulation of PTP1B.
@en
prefLabel
Live-cell imaging of enzyme-substrate interaction reveals spatial regulation of PTP1B.
@en
P2093
P356
P1433
P1476
Live-cell imaging of enzyme-substrate interaction reveals spatial regulation of PTP1B
@en
P2093
Ali Kinkhabwala
Andreas Schleifenbaum
Benjamin G Neel
Philippe I H Bastiaens
P304
P356
10.1126/SCIENCE.1134966
P407
P577
2007-01-01T00:00:00Z