Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression.
about
Recent progress in the study of methylated tumor suppressor genes in gastric cancerSmad4-mediated TGF-beta signaling in tumorigenesis.Genetic Alterations in Gastric Cancer Associated with Helicobacter pylori Infection.Meta-analysis of the prognostic value of smad4 immunohistochemistry in various cancers.Functional screening for miRNAs targeting Smad4 identified miR-199a as a negative regulator of TGF-β signalling pathway.Genetic variations in the SMAD4 gene and gastric cancer susceptibilityActivation of miR-21 by STAT3 induces proliferation and suppresses apoptosis in nasopharyngeal carcinoma by targeting PTEN geneCooperativity of E-cadherin and Smad4 loss to promote diffuse-type gastric adenocarcinoma and metastasis.Low SP1 expression differentially affects intestinal-type compared with diffuse-type gastric adenocarcinomaDiscovery of SMAD4 promoters, transcription factor binding sites and deletions in juvenile polyposis patients.Identification of germline alterations of the mad homology 2 domain of SMAD3 and SMAD4 from the Ontario site of the breast cancer family registry (CFR)Expression of Smad4, TGF-βRII, and p21(waf1) in esophageal squamous cell carcinoma tissue.Dual targeting of retinoid X receptor and histone deacetylase with DW22 as a novel antitumor approach.SMAD4 expression in breast ductal carcinoma correlates with prognosis.Cooperatively transcriptional and epigenetic regulation of sonic hedgehog overexpression drives malignant potential of breast cancer.DPC4 expression in the small intestinal adenocarcinomas.Mutations in the TGF-β repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysmTob1 induces apoptosis and inhibits proliferation, migration and invasion of gastric cancer cells by activating Smad4 and inhibiting β‑catenin signalingGastric tumor development in Smad3-deficient mice initiates from forestomach/glandular transition zone along the lesser curvature.Sleeping Beauty transposon mutagenesis identifies genes that cooperate with mutant Smad4 in gastric cancer development.Smad3 and phospho-Smad3 are potential markers of invasive nonfunctioning pituitary adenomas.Chronic TGFβ stimulation promotes the metastatic potential of lung cancer cells by Snail protein stabilization through integrin β3-Akt-GSK3β signalingUp-regulation of miR-224 promotes cancer cell proliferation and invasion and predicts relapse of colorectal cancer.Inhibition of pancreatic carcinoma cell growth in vitro by DPC4 gene transfection.Epstein-Barr virus BARF1-induced NFκB/miR-146a/SMAD4 alterations in stomach cancer cells.The expression of TGF-β1, Smad3, phospho-Smad3 and Smad7 is correlated with the development and invasion of nonfunctioning pituitary adenomas.Activation of an AKT/FOXM1/STMN1 pathway drives resistance to tyrosine kinase inhibitors in lung cancer.MicroRNA-1285-5p influences the proliferation and metastasis of non-small-cell lung carcinoma cells via downregulating CDH1 and Smad4.Upregulated SMAD3 promotes epithelial-mesenchymal transition and predicts poor prognosis in pancreatic ductal adenocarcinoma.Claudin-4 overexpression is associated with epigenetic derepression in gastric carcinoma.Massive gastric juvenile-type polyposis: a clinicopathological analysis of 22 cases.Short Communication: Studying the Role of Smart Flare Gold Nano Particles in Studying Micro RNA and Oncogene Differential Expression in Prostate Cancer Cell Lines.Concordant repression and aberrant methylation of transforming growth factor-beta signaling pathway genes occurs early in gastric cardia adenocarcinoma.Hepatitis B virus X protein induces the expression of MTA1 and HDAC1, which enhances hypoxia signaling in hepatocellular carcinoma cells.Hypoxia-induced endothelial-mesenchymal transition is associated with RASAL1 promoter hypermethylation in human coronary endothelial cells.Preliminary Study of the Role F-Box Protein 32 (FBXO32) in Colorectal Neoplasms Through the Transforming Growth Factor beta (TGF-β)/Smad4 Signalling Pathway.miR-324-3p promotes gastric cancer development by activating Smad4-mediated Wnt/beta-catenin signaling pathway.miR-146a promotes cell migration and invasion in melanoma by directly targeting SMAD4.Whole-genome sequencing of esophageal adenocarcinoma in Chinese patients reveals distinct mutational signatures and genomic alterations
P2860
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P2860
Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression.
@en
type
label
Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression.
@en
prefLabel
Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression.
@en
P2093
P1476
Inactivation of SMAD4 tumor suppressor gene during gastric carcinoma progression.
@en
P2093
Chun-Fu Wu
Jung Hyun Lee
Li-Hui Wang
Seok-Hyung Kim
Tae Sung Park
Yoon-La Choi
Young Chul Kim
Young Kee Shin
Yun-Chul Hong
P304
P356
10.1158/1078-0432.CCR-06-1467
P407
P577
2007-01-01T00:00:00Z