Novel DNA lesions generated by the interaction between therapeutic thiopurines and UVA light.
about
Skin cancer in organ transplant recipients: effects of immunosuppressive medications on DNA repairActivation of p38 MAP kinase and JNK pathways by UVA irradiationCrosslinking of DNA repair and replication proteins to DNA in cells treated with 6-thioguanine and UVATranslesion DNA synthesis and mutagenesis in prokaryotes.Thiopurines in current medical practice: molecular mechanisms and contributions to therapy-related cancer.Direct observation and quantitative characterization of singlet oxygen in aqueous solution upon UVA excitation of 6-thioguanines.Immune profiling and cancer post transplantationOral azathioprine leads to higher incorporation of 6-thioguanine in DNA of skin than liver: the protective role of the Keap1/Nrf2/ARE pathway.Quantification of Thiopurine/UVA-Induced Singlet Oxygen ProductionIdentification of potentially cytotoxic lesions induced by UVA photoactivation of DNA 4-thiothymidine in human cellsOxidative Damage to RPA Limits the Nucleotide Excision Repair Capacity of Human CellsIn vitro replication and thermodynamic studies of methylation and oxidation modifications of 6-thioguanine.High mobility group protein B1 is an activator of apoptotic response to antimetabolite drugs.PTCH mutations in basal cell carcinomas from azathioprine-treated organ transplant recipients.Reactive oxygen species generated by thiopurine/UVA cause irreparable transcription-blocking DNA lesions.6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo.Enzymatic synthesis and phosphorolysis of 4(2)-thioxo- and 6(5)-azapyrimidine nucleosides by E. coli nucleoside phosphorylasesUVA photosensitization of thiopurines and skin cancer in organ transplant recipients.4-Thiothymidine sensitization of DNA to UVA offers potential for a novel photochemotherapy.Multiple forms of DNA damage caused by UVA photoactivation of DNA 6-thioguanine.Photoinduced damage to cellular DNA: direct and photosensitized reactions.A practical guide to the use of thiopurines in oral medicine.DNA repair inhibition by UVA photoactivated fluoroquinolones and vemurafenib.Formation and repair of oxidatively generated damage in cellular DNA.Oxidatively-generated damage to DNA and proteins mediated by photosensitized UVASkin Cancers in Organ Transplant Recipients.Known and potential new risk factors for skin cancer in European populations: a multicentre case-control study.Guanine sulphinate is a major stable product of photochemical oxidation of DNA 6-thioguanine by UVA irradiation.Immune effector cells produce lethal DNA damage in cells treated with a thiopurineReactive oxygen-mediated damage to a human DNA replication and repair protein.Mutagenic and cytotoxic properties of 6-thioguanine, S6-methylthioguanine, and guanine-S6-sulfonic acid.Rose Bengal-photosensitized oxidation of 4-thiothymidine in aqueous medium: evidence for the reaction of the nucleoside with singlet state oxygen.MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation.Photosensitized UVA-Induced Cross-Linking between Human DNA Repair and Replication Proteins and DNA Revealed by Proteomic Analysis.DNA breakage and cell cycle checkpoint abrogation induced by a therapeutic thiopurine and UVA radiationAzathioprine treatment photosensitizes human skin to ultraviolet A radiation.Use of thiopurines in the treatment of inflammatory bowel disease is associated with an increased risk of non-melanoma skin cancer in an at-risk population: a cohort study.Decoding the Molecular Basis for the Population Mechanism of the Triplet Phototoxic Precursors in UVA Light-Activated Pyrimidine Anticancer Drugs.The excited-state decay mechanism of 2,4-dithiothymine in the gas phase, microsolvated surroundings, and aqueous solution.2-Thiouracil intersystem crossing photodynamics studied by wavelength-dependent photoelectron and transient absorption spectroscopies.
P2860
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P2860
Novel DNA lesions generated by the interaction between therapeutic thiopurines and UVA light.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Novel DNA lesions generated by ...... tic thiopurines and UVA light.
@en
type
label
Novel DNA lesions generated by ...... tic thiopurines and UVA light.
@en
prefLabel
Novel DNA lesions generated by ...... tic thiopurines and UVA light.
@en
P2093
P1433
P1476
Novel DNA lesions generated by ...... tic thiopurines and UVA light.
@en
P2093
Conal M Perrett
Graham Jeffs
Peter Karran
Peter O'Donovan
Xiaohong Zhang
Xiaolin Ren
P304
P356
10.1016/J.DNAREP.2006.11.003
P577
2006-12-22T00:00:00Z