about
The CDK9 C-helix Exhibits Conformational Plasticity That May Explain the Selectivity of CAN508Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1ARC (NSC 188491) has identical activity to Sangivamycin (NSC 65346) including inhibition of both P-TEFb and PKC.Brain dysfunction in the era of combination antiretroviral therapy: implications for the treatment of the aging population of HIV-infected individualsProtein phosphatase-1 activates CDK9 by dephosphorylating Ser175.Iron chelators of the di-2-pyridylketone thiosemicarbazone and 2-benzoylpyridine thiosemicarbazone series inhibit HIV-1 transcription: identification of novel cellular targets--iron, cyclin-dependent kinase (CDK) 2, and CDK9Expression of a protein phosphatase 1 inhibitor, cdNIPP1, increases CDK9 threonine 186 phosphorylation and inhibits HIV-1 transcription1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription.Iron chelators ICL670 and 311 inhibit HIV-1 transcription.Role of cellular iron and oxygen in the regulation of HIV-1 infection.Regulation of HIV-1 transcription at 3% versus 21% oxygen concentrationDifferential sensitivity of human colon cancer cell lines to the nucleoside analogs ARC and DRB.Pyrrolo[2,3-d]pyrimidine (7-deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides.
P2860
Q27676963-3600C329-0D84-4548-8B25-DEA470B1F544Q28480912-8D75653E-3296-4CCA-B3CA-8427A7FDE07AQ30486336-6058B8B3-BEF7-4A53-B0AA-7CD66248B03AQ33614467-FB69CBA6-E728-4DBF-AA10-42B560098553Q33886004-4FB19B6C-161C-4251-AE3D-F0D9B4E0815FQ34458484-86EF07E9-1E76-4A6A-ACD6-0150AF0CF524Q34537015-92CEB6F0-58EA-483F-A8A5-BFEDDB664E28Q34619456-CB8903B7-4E10-45B7-AB53-2B3B383A8A91Q36143645-7DD01425-F8AE-4DE5-9936-3B2C3220C920Q36839068-663542A5-4CC8-4A1A-9345-7508B356CF15Q37423506-4656FC0F-9566-4FB9-9445-6667240F79F7Q40052641-05B3F2E3-4332-460D-8091-033F4FEE8032Q47095447-4BF65559-E127-433B-8AF1-371E37BE948D
P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
A novel anticancer agent ARC antagonizes HIV-1 and HCV.
@en
type
label
A novel anticancer agent ARC antagonizes HIV-1 and HCV.
@en
prefLabel
A novel anticancer agent ARC antagonizes HIV-1 and HCV.
@en
P2093
P2860
P356
P1433
P1476
A novel anticancer agent ARC antagonizes HIV-1 and HCV
@en
P2093
A L Gartel
M Jerebtsova
T Ammosova
T J Layden
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210158
P407
P577
2006-12-18T00:00:00Z
P5875
P6179
1031624582