GammaH2AX in cancer cells: a potential biomarker for cancer diagnostics, prediction and recurrence.
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Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinomaExpression and functionality of histone H2A variants in cancerUse of the γ-H2AX assay to monitor DNA damage and repair in translational cancer researchGammaH2AX and cancerEvaluation of Severe Combined Immunodeficiency and Combined Immunodeficiency Pediatric Patients on the Basis of Cellular Radiosensitivity.Phase I study of olaparib in combination with liposomal doxorubicin in patients with advanced solid tumours.Imaging the DNA damage response with PET and SPECTTelomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells.Dynamic In Vivo Profiling of DNA Damage and Repair after Radiotherapy Using Canine Patients as a Model.H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy.Role of oxidatively induced DNA lesions in human pathogenesisHistone gammaH2AX and poly(ADP-ribose) as clinical pharmacodynamic biomarkers.Development of a validated immunofluorescence assay for γH2AX as a pharmacodynamic marker of topoisomerase I inhibitor activity.Age-related disease association of endogenous γ-H2AX foci in mononuclear cells derived from leukapheresis.Evaluation of the efficacy of radiation-modifying compounds using γH2AX as a molecular marker of DNA double-strand breaksEpigenetic changes and nontargeted radiation effects--is there a link?Human APOBEC3A isoforms translocate to the nucleus and induce DNA double strand breaks leading to cell stress and death.H2AX: functional roles and potential applications.Imaging DNA damage in vivo using gammaH2AX-targeted immunoconjugatesAltered radiation responses of breast cancer cells resistant to hormonal therapyInduction and persistence of radiation-induced DNA damage is more pronounced in young animals than in old animalsThe ups and downs of DNA repair biomarkers for PARP inhibitor therapiesγ-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1α/VEGF pathways under hypoxic condition.Epigenetic Modifications and Accumulation of DNA Double-Strand Breaks in Oral Lichen Planus Lesions Presenting Poor Response to Therapy.Activity of the DNA minor groove cross-linking agent SG2000 (SJG-136) against canine tumours.Dysregulation of PAK1 Is Associated with DNA Damage and Is of Prognostic Importance in Primary Esophageal Small Cell Carcinoma.Phospho-histone H2AX is a diagnostic and prognostic marker for epithelial ovarian cancerH2AX phosphorylation at the sites of DNA double-strand breaks in cultivated mammalian cells and tissues.γ-H2AX and other histone post-translational modifications in the clinic.DNA Damage Response Assessments in Human Tumor Samples Provide Functional Biomarkers of Radiosensitivity.Individual and Combined Expression of DNA Damage Response Molecules PARP1, γH2AX, BRCA1, and BRCA2 Predict Shorter Survival of Soft Tissue Sarcoma Patients.90Y-daclizumab, an anti-CD25 monoclonal antibody, provided responses in 50% of patients with relapsed Hodgkin's lymphomaTumor-targeted and pH-controlled delivery of doxorubicin using gold nanorods for lung cancer therapy.Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assayIdentification of WEE1 as a potential molecular target in cancer cells by RNAi screening of the human tyrosine kinome.Formation of telomeric repeat-containing RNA (TERRA) foci in highly proliferating mouse cerebellar neuronal progenitors and medulloblastoma.DNA double-strand break repair: a theoretical framework and its application.Predictive significance of DNA damage and repair biomarkers in triple-negative breast cancer patients treated with neoadjuvant chemotherapy: An exploratory analysis.Histone H2AX phosphorylation as a measure of DNA double-strand breaks and a marker of environmental stress and disease activity in lupus.γ-H2AX as a biomarker of DNA damage induced by ionizing radiation in human peripheral blood lymphocytes and artificial skin.
P2860
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P2860
GammaH2AX in cancer cells: a potential biomarker for cancer diagnostics, prediction and recurrence.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
GammaH2AX in cancer cells: a p ...... cs, prediction and recurrence.
@en
type
label
GammaH2AX in cancer cells: a p ...... cs, prediction and recurrence.
@en
prefLabel
GammaH2AX in cancer cells: a p ...... cs, prediction and recurrence.
@en
P356
P1433
P1476
GammaH2AX in cancer cells: a p ...... cs, prediction and recurrence.
@en
P2093
Olga A Sedelnikova
William M Bonner
P304
P356
10.4161/CC.5.24.3569
P577
2006-12-15T00:00:00Z