A comparative study of different vector designs for the mammalian expression of recombinant IgG antibodies.
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Posttranslational Modifications and the Immunogenicity of BiotherapeuticsDevelopment of human antibody fragments using antibody phage display for the detection and diagnosis of Venezuelan equine encephalitis virus (VEEV)Comparison of internal ribosome entry site (IRES) and Furin-2A (F2A) for monoclonal antibody expression level and quality in CHO cellsIdentification of a novel temperature sensitive promoter in CHO cells.Persistent expression of biologically active anti-HER2 antibody by AAVrh.10-mediated gene transferThe influence of antibody fragment format on phage display based affinity maturation of IgG.Balancing the Expression and Production of a Heterodimeric Protein: Recombinant Agkisacutacin as a Novel Antithrombotic Drug CandidateA Human Anti-Toll Like Receptor 4 Fab Fragment Inhibits Lipopolysaccharide-Induced Pro-Inflammatory Cytokines Production in Macrophages.The Fab Fragment of a Human Anti-Siglec-9 Monoclonal Antibody Suppresses LPS-Induced Inflammatory Responses in Human MacrophagesEvaluating the expression profile and stability of different UCOE containing vector combinations in mAb-producing CHO cellsAlternative-splicing-based bicistronic vectors for ratio-controlled protein expression and application to recombinant antibody production.Expression of recombinant antibodies.A short synthetic chimeric sequence harboring matrix attachment region/PSAR2 increases transgene expression in Chinese hamster ovary cells.Laboratory Scale Production and Purification of a Therapeutic Antibody.Surface display vectors for selective detection and isolation of high level antibody producing cells.Oligomeric forms of single chain immunoglobulin (scIgG).Overexpression of CHOP alone and in combination with chaperones is effective in improving antibody production in mammalian cells.Mechanism of gene transfection by polyamidoamine (PAMAM) dendrimers modified with ornithine residues.In vitro and in vivo comparison of viral and cellular internal ribosome entry sites for bicistronic vector expression.Efficient expression from one CMV enhancer controlling two core promoters.Improvement of reporter activity by IRES-mediated polycistronic reporter system.Monoclonal antibodies expression improvement in CHO cells by PiggyBac transposition regarding vectors ratios and design.Expression of antibodies using single open reading frame (sORF) vector design: Demonstration of manufacturing feasibility.Cleavage efficient 2A peptides for high level monoclonal antibody expression in CHO cells.Scaling-up and production of therapeutic antibodies for preclinical studies.Maximizing antibody production in suspension-cultured mammalian cells by the customized transient gene expression method.Impact of gene vector design on the control of recombinant monoclonal antibody production by Chinese hamster ovary cells.The emerging role of systems biology for engineering protein production in CHO cells.Antitumor activity of a newly developed monoclonal antibody against ROR1 in ovarian cancer cells.Electrostatic engineering of the interface between heavy and light chains promotes antibody Fab fragment production.
P2860
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P2860
A comparative study of different vector designs for the mammalian expression of recombinant IgG antibodies.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
A comparative study of differe ...... of recombinant IgG antibodies.
@en
type
label
A comparative study of differe ...... of recombinant IgG antibodies.
@en
prefLabel
A comparative study of differe ...... of recombinant IgG antibodies.
@en
P2093
P1476
A comparative study of differe ...... of recombinant IgG antibodies.
@en
P2093
Christian Menzel
Congcong Zhang
Doris Meier
Jiandong Li
Thomas Jostock
P304
P356
10.1016/J.JIM.2006.10.010
P50
P577
2006-11-13T00:00:00Z