Bisindolylmaleimide I suppresses fibroblast growth factor-mediated activation of Erk MAP kinase in chondrocytes by preventing Shp2 association with the Frs2 and Gab1 adaptor proteins.
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Sixteen years and counting: the current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasiasMeclozine facilitates proliferation and differentiation of chondrocytes by attenuating abnormally activated FGFR3 signaling in achondroplasiaNF449 is a novel inhibitor of fibroblast growth factor receptor 3 (FGFR3) signaling active in chondrocytes and multiple myeloma cellsAnalysis of STAT1 activation by six FGFR3 mutants associated with skeletal dysplasia undermines dominant role of STAT1 in FGFR3 signaling in cartilageExtracellular Signal-Regulated Kinase Signaling in CD4-Expressing Cells Inhibits Osteochondromas.Mechanical activation of mammalian target of rapamycin pathway is required for cartilage development.FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling.Fibroblast growth factor 2-stimulated proliferation is lower in muscle precursor cells from old ratsFGFR3/fibroblast growth factor receptor 3 inhibits autophagy through decreasing the ATG12-ATG5 conjugate, leading to the delay of cartilage development in achondroplasiaFGFR3 promotes synchondrosis closure and fusion of ossification centers through the MAPK pathwayMolecular pathology of the fibroblast growth factor family.Fibroblast growth factor receptor 3 interacts with and activates TGFβ-activated kinase 1 tyrosine phosphorylation and NFκB signaling in multiple myeloma and bladder cancer.A novel interaction between fibroblast growth factor receptor 3 and the p85 subunit of phosphoinositide 3-kinase: activation-dependent regulation of ERK by p85 in multiple myeloma cells.Regulation of rod photoreceptor differentiation by STAT3 is controlled by a tyrosine phosphatase.Post-translational modifications regulate signalling by Ror1.Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR catalytic activity for therapy of short-stature syndromes.Fibroblast growth factor receptor 1 is a key inhibitor of TGFβ signaling in the endothelium.Fibroblast Growth Factor 2 and Its Receptors in Bone Biology and Disease.
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Bisindolylmaleimide I suppresses fibroblast growth factor-mediated activation of Erk MAP kinase in chondrocytes by preventing Shp2 association with the Frs2 and Gab1 adaptor proteins.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Bisindolylmaleimide I suppress ...... rs2 and Gab1 adaptor proteins.
@en
type
label
Bisindolylmaleimide I suppress ...... rs2 and Gab1 adaptor proteins.
@en
prefLabel
Bisindolylmaleimide I suppress ...... rs2 and Gab1 adaptor proteins.
@en
P2093
P2860
P50
P356
P1476
Bisindolylmaleimide I suppress ...... rs2 and Gab1 adaptor proteins.
@en
P2093
Claire Farrington-Rock
Leslie Michels Thompson
Lisa Salazar
William R Wilcox
P2860
P304
P356
10.1074/JBC.M606144200
P407
P577
2006-12-04T00:00:00Z