about
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and BeyondModification of eukaryotic initiation factor 5A from Plasmodium vivax by a truncated deoxyhypusine synthase from Plasmodium falciparum: An enzyme with dual enzymatic propertiesDeoxyhypusine hydroxylase from Plasmodium vivax, the neglected human malaria parasite: molecular cloning, expression and specific inhibition by the 5-LOX inhibitor zileutonA Putative Non-Canonical Ras-Like GTPase from P. falciparum: Chemical Properties and Characterization of the ProteinCloning, expression and functional activity of deoxyhypusine synthase from Plasmodium vivax.In vitro and in vivo silencing of plasmodial dhs and eIf-5a genes in a putative, non-canonical RNAi-related pathway.The guanylhydrazone CNI-1493: an inhibitor with dual activity against malaria-inhibition of host cell pro-inflammatory cytokine release and parasitic deoxyhypusine synthase.In Vitro and In Vivo Antimalarial Activity Assays of Seeds from Balanites aegyptiaca: Compounds of the Extract Show Growth Inhibition and Activity against Plasmodial Aminopeptidase.Spermidine metabolism in parasitic protozoa--a comparison to the situation in prokaryotes, viruses, plants and fungi.Therapy of uncomplicated falciparum malaria in Europe: MALTHER - a prospective observational multicentre study.Inhibition of hypusine biosynthesis in plasmodium: a possible, new strategy in prevention and therapy of malaria.Anthracene-polyamine conjugates inhibit in vitro proliferation of intraerythrocytic Plasmodium falciparum parasitesA suggested vital function for eIF-5A and dhs genes during murine malaria blood-stage infectionAssessment of deoxyhypusine hydroxylase as a putative, novel drug target.Translational control of eIF5A in various diseases.Chemical profiling of deoxyhypusine hydroxylase inhibitors for antimalarial therapy.Targeting enzymes involved in spermidine metabolism of parasitic protozoa--a possible new strategy for anti-parasitic treatment.In search of novel agents for therapy of tropical diseases and human immunodeficiency virus.Completing the hypusine pathway in Plasmodium.Target evaluation of deoxyhypusine synthase from Theileria parva the neglected animal parasite and its relationship to Plasmodium.The efficacy of inhibitors involved in spermidine metabolism in Plasmodium falciparum, Anopheles stephensi and Trypanosoma evansi.Effect of drugs inhibiting spermidine biosynthesis and metabolism on the in vitro development of Plasmodium falciparum.Rapid stimulation of a soybean protein-serine kinase that phosphorylates a novel bZIP DNA-binding protein, G/HBF-1, during the induction of early transcription-dependent defenses.Cloning and expression of a cDNA encoding homospermidine synthase from Senecio vulgaris (Asteraceae) in Escherichia coli.Chlorella virus PBCV-1 encodes a functional homospermidine synthase.Down-regulation of hypusine biosynthesis in Plasmodium by inhibition of S-adenosyl-methionine-decarboxylase.Heterologous expression of a bacterial homospermidine synthase gene in transgenic tobacco: effects on the polyamine pathway.[New strategies in therapy to roll back malaria].[Diclofenac caused renal insufficiency. A case illustrating the necessity of pharmaceutical intervention and care].[A new, sixth human malaria parasite].A rapid and robust assay for the determination of the amino acid hypusine as a possible biomarker for a high-throughput screening of antimalarials and for the diagnosis and therapy of different diseases.Piperidones with activity against Plasmodium falciparum.The role of isochorismic acid in primary and secondary metabolismRole of the entC gene in enterobactin and menaquinone biosynthesis in Escherichia coliInhibition of EIF-5A prevents apoptosis in human cardiomyocytes after malaria infection
P50
Q27826351-A313DE3A-5436-4462-AD8E-0D14F9EE1531Q27974776-3ADE84C2-9B9C-4239-A440-731180CEC539Q28487727-F9E45B97-021C-4A96-9A42-AD100F42B697Q28550705-2C9FC7FA-E688-4C7D-862E-ECC3C972F4AAQ33260506-2D69D859-8205-40B6-AA58-3038544FE23AQ34303004-54F010D4-8D2E-4D71-A5F1-E665ED79C075Q34747260-94650D81-AE02-4207-B2D1-65D0A55B80C5Q35038871-5C8EB2E1-D0B9-4D5C-A8DF-3B2956D2E584Q35123369-C00F32C7-4589-4282-9EDD-72F6CBEA0369Q36334960-9665C1EB-A8E3-4951-ABF2-2BCB7AFB891CQ36651974-90CB9C6F-CBB9-48DA-AB5A-135D1A2322D6Q37026599-78BF5E35-60C3-4015-BAFD-405AFC724686Q37148810-088A31B5-48F0-4920-B567-F5538ED5BB81Q37643529-AF2EE323-8FD6-42DA-89B0-8DB828EFF70FQ37912041-E8C3E543-250D-427A-A78C-217D79D1C2DEQ38128748-FF8402EB-DC34-43C1-930C-0B83FB7CFC9EQ38349539-F5EA7308-4221-4596-8EC0-2911639C2954Q39026059-5591E47B-3734-4763-87BB-804E8E246B86Q39899740-82F1F9C0-1CF2-426A-A5DD-452C212DBD2BQ40204341-F22589C6-D6F7-4C4C-ABD8-13B7189971B5Q41913679-DB58C50E-EB9E-448E-9DD8-4C147775ACA5Q41918346-2CF45021-47CF-41D5-8126-4C8E6375BFE5Q42157657-179F7530-44B4-4A2C-99F2-0DD1449BA375Q42609330-D444FB90-BA88-4D1A-A28E-AA82AC6049BAQ42612810-1468CB8E-0F96-4EEE-B4CE-A9A821D362A7Q43233338-7BCC28FF-15FB-4821-8BC4-9D1D980C73C0Q44060050-D503BE6F-4A3C-4457-84AC-C9C49917042CQ44080021-E5FDA2AF-06EE-438E-A239-63A74F2E59D5Q44678091-DDE9022E-0C6F-4B20-931F-46CAEEC1A9B2Q47945930-08379386-C84B-4DCE-9CC0-408C3BA8B0FBQ47973770-379B28D6-A1DF-4E0D-B7F3-E9666A8C15A3Q48025917-0BB945DE-6858-43BA-BD7D-821FCD1E5BB1Q60998424-EEE7509A-186F-4EE2-92B3-8E12F7F9A3FAQ60998425-8FFB1E10-5862-4345-B9F4-D1DF6ACEC54CQ94523327-59A74283-9CA7-4EA9-A285-709B00EF88E4
P50
description
hulumtuese
@sq
researcher
@en
ricercatrice
@it
wetenschapper
@nl
հետազոտող
@hy
name
Annette Kaiser
@ast
Annette Kaiser
@en
Annette Kaiser
@es
Annette Kaiser
@nl
type
label
Annette Kaiser
@ast
Annette Kaiser
@en
Annette Kaiser
@es
Annette Kaiser
@nl
prefLabel
Annette Kaiser
@ast
Annette Kaiser
@en
Annette Kaiser
@es
Annette Kaiser
@nl
P106
P21
P214
194146462687627772145
P31
P496
0000-0001-7873-3958