Analysis of the structure-activity relationship of four herpesviral UL97 subfamily protein kinases reveals partial but not full functional conservation.
about
Cyclin-dependent kinase-like function is shared by the beta- and gamma- subset of the conserved herpesvirus protein kinasesA locus encompassing the Epstein-Barr virus bglf4 kinase regulates expression of genes encoding viral structural proteinsInactivation and disassembly of the anaphase-promoting complex during human cytomegalovirus infection is associated with degradation of the APC5 and APC4 subunits and does not require UL97-mediated phosphorylation of Cdh1.Human cytomegalovirus UL97 kinase and nonkinase functions mediate viral cytoplasmic secondary envelopment.Conserved herpesvirus kinases target the DNA damage response pathway and TIP60 histone acetyltransferase to promote virus replication.The UL13 and US3 Protein Kinases of Herpes Simplex Virus 1 Cooperate to Promote the Assembly and Release of Mature, Infectious Virions.The Emerging Roles of Viroporins in ER Stress Response and Autophagy Induction during Virus InfectionSites and roles of phosphorylation of the human cytomegalovirus DNA polymerase subunit UL44.Key motifs in EBV (Epstein-Barr virus)-encoded protein kinase for phosphorylation activity and nuclear localization.Conserved herpesvirus protein kinases.Cyclin-dependent Kinases Phosphorylate the Cytomegalovirus RNA Export Protein pUL69 and Modulate Its Nuclear Localization and Activity.Protein array identification of substrates of the Epstein-Barr virus protein kinase BGLF4Expression of the human cytomegalovirus UL97 gene in a chimeric guinea pig cytomegalovirus (GPCMV) results in viable virus with increased susceptibility to ganciclovir and maribavir.Function of human cytomegalovirus UL97 kinase in viral infection and its inhibition by maribavir.Molecular targets for antiviral therapy of cytomegalovirus infections.Interactome mapping: using protein microarray technology to reconstruct diverse protein networks.Viral serine/threonine protein kinasesThe cyclin-dependent kinase ortholog pUL97 of human cytomegalovirus interacts with cyclinsProteomic Interaction Patterns between Human Cyclins, the Cyclin-Dependent Kinase Ortholog pUL97 and Additional Cytomegalovirus Proteins.The Epstein-Barr virus (EBV)-encoded protein kinase, EBV-PK, but not the thymidine kinase (EBV-TK), is required for ganciclovir and acyclovir inhibition of lytic viral productionSimian virus 40 T/t antigens and lamin A/C small interfering RNA rescue the phenotype of an Epstein-Barr virus protein kinase (BGLF4) mutant.Maribavir inhibits epstein-barr virus transcription in addition to viral DNA replicationPhosphorylation of retinoblastoma protein by viral protein with cyclin-dependent kinase function.The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase DomainA new mutation in the human cytomegalovirus UL97 gene may confer ganciclovir resistance in Chinese kidney transplant recipients.Direct Substrate Identification with an Analog Sensitive (AS) Viral Cyclin-Dependent Kinase (v-Cdk).
P2860
Q28475457-7ECA2F93-D5B6-4DE6-9324-7ECD13647A69Q34105467-E9F6F715-4F04-4C54-966F-B6EA4D5DA997Q34178268-ABCFD203-83C3-41F8-B4B7-210614931C46Q34742654-DE4A9794-824B-427F-AD08-47D7BC9AA6B9Q35660314-F6542290-EA24-485B-84FA-AC9D7BD45DEDQ35675713-F3008268-E827-4297-B0B0-09EC67221F06Q35808638-DFA68F52-F864-4447-84F0-8CFB70770817Q36212341-36DE28B7-87E7-449A-A531-55915D3E3908Q36399836-51B2238B-1914-428D-BA79-3A0568158BD9Q36491044-61453BC7-44B8-43B6-AE80-7A556F26A546Q37136798-4A6824D3-ABDE-4853-87B2-41F170931E31Q37192108-B7B286B4-96E1-4860-B5F3-C2F2184822A0Q37453329-D6DD318E-91EE-46B7-B08A-8222515B3656Q37478310-FD511906-E73A-44C5-9A3A-9EBA7D9959A3Q37573779-33DB5620-AAC7-458E-B540-90E43EA47F95Q37671058-950A3B9B-6CDA-47FD-AACE-4E47A3262B21Q37810382-04469609-8A0E-4974-823F-3D14EB63B679Q38534801-7D4B2BE6-F594-4310-BBE7-409FEDDD735EQ39467030-6B5860A3-8A1D-4021-A87A-D887BCC2C1E0Q39735571-7DA12A34-9920-4B71-AD1C-E2B8D307C16AQ39741182-EBCB3859-A35C-444D-8916-0EEF8A8D389FQ39798789-66AF7D5A-CE77-45E2-AF5C-A99D966F13DEQ39984081-4C7AB866-DF46-4848-97A8-E5667CA6C368Q41485874-0DBB7E7B-2BD0-4EEF-B8BB-92F6E6AAF9E5Q46490890-6D175067-B73A-4A48-B027-079E2EB06C64Q47319898-85E7B3CF-DBD5-45A3-8E6E-96912E8B2DBF
P2860
Analysis of the structure-activity relationship of four herpesviral UL97 subfamily protein kinases reveals partial but not full functional conservation.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Analysis of the structure-acti ...... full functional conservation.
@en
type
label
Analysis of the structure-acti ...... full functional conservation.
@en
prefLabel
Analysis of the structure-acti ...... full functional conservation.
@en
P2093
P356
P1476
Analysis of the structure-acti ...... full functional conservation.
@en
P2093
Daniel Romaker
Katja Maurer
Manfred Marschall
Sabrina Auerochs
Vera Schregel
P304
P356
10.1021/JM060696S
P407
P577
2006-11-01T00:00:00Z