Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics.
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Interferon lambda: a new sword in cancer immunotherapyA new insight into hepatitis C vaccine developmentIFNL3 mRNA structure is remodeled by a functional non-coding polymorphism associated with hepatitis C virus clearanceVaccination for hepatitis C virus: closing in on an evasive targetA variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virusGenetic variation in IL28B and spontaneous clearance of hepatitis C virusPurification, crystallization and preliminary crystallographic studies of the complex of interferon-lambda1 with its receptorInterleukin-29 functions cooperatively with interferon to induce antiviral gene expression and inhibit hepatitis C virus replicationIFNalpha and IFNlambda differ in their antiproliferative effects and duration of JAK/STAT signaling activityINTERFEROME: the database of interferon regulated genesIdentification of three interferon-inducible cellular enzymes that inhibit the replication of hepatitis C virusThe zinc finger antiviral protein acts synergistically with an interferon-induced factor for maximal activity against alphavirusesInterferon (IFN) and Cellular Immune Response Evoked in RNA-Pattern Sensing During Infection with Hepatitis C Virus (HCV)Interferon-λ: Immune Functions at Barrier Surfaces and BeyondRegulation of hepatic innate immunity by hepatitis C virusSTAT proteins - key regulators of anti-viral responses, inflammation, and tumorigenesis in the liverEmerging concepts in immunity to hepatitis C virus infection.Genetic variants at the IFNL3 locus and their association with hepatitis C virus infections reveal novel insights into host-virus interactionsInnate immune responses in hepatitis C virus infectionComparison of antiviral activity of lambda-interferons against HIV replication in macrophagesAntiviral effect of interferon lambda against West Nile virusHepatitis C: recent successes and continuing challenges in the development of improved treatment modalitiesInterferon- Is Functionally an Interferon but Structurally Related to the Interleukin-10 FamilyCrystal Structure of Human Interferon-λ1 in Complex with Its High-Affinity Receptor Interferon-λR1Interferon-lambdas: the modulators of antivirus, antitumor, and immune responsesInterferon-λ4 is a cell-autonomous type III interferon associated with pre-treatment hepatitis C virus burdenIL28B, HLA-C, and KIR variants additively predict response to therapy in chronic hepatitis C virus infection in a European Cohort: a cross-sectional studyFemale sex and IL28B, a synergism for spontaneous viral clearance in hepatitis C virus (HCV) seroconverters from a community-based cohortAdvanced molecular surveillance of hepatitis C virusAn IL28B genotype-based clinical prediction model for treatment of chronic hepatitis CTranscriptional regulation of IFN-λ genes in hepatitis C virus-infected hepatocytes via IRF-3·IRF-7·NF-κB complexMultiple interferon stimulated genes synergize with the zinc finger antiviral protein to mediate anti-alphavirus activity.Safety, Tolerability, and Immunogenicity of InterferonsThe bacterial pathogen Listeria monocytogenes and the interferon family: type I, type II and type III interferonsIFN-λ receptor 1 expression is induced in chronic hepatitis C and correlates with the IFN-λ3 genotype and with nonresponsiveness to IFN-α therapiesIFNL3/4 genotype is associated with altered immune cell populations in peripheral blood in chronic hepatitis C infectionInterferon induction of IFITM proteins promotes infection by human coronavirus OC43Viral induction of the zinc finger antiviral protein is IRF3-dependent but NF-kappaB-independent.Hepatitis B Virus e Antigen Activates the Suppressor of Cytokine Signaling 2 to Repress Interferon Action.Peg-Interferon Lambda Treatment Induces Robust Innate and Adaptive Immunity in Chronic Hepatitis B Patients.
P2860
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P2860
Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Interferons alpha and lambda i ...... and gene regulation kinetics.
@en
type
label
Interferons alpha and lambda i ...... and gene regulation kinetics.
@en
prefLabel
Interferons alpha and lambda i ...... and gene regulation kinetics.
@en
P2093
P1433
P1476
Interferons alpha and lambda i ...... and gene regulation kinetics.
@en
P2093
Arash Grakoui
Charles M Rice
Erica S Machlin
Margaret R MacDonald
Sergei V Kotenko
Tobias Marcello
P304
P356
10.1053/J.GASTRO.2006.09.052
P407
P577
2006-10-01T00:00:00Z