Orexin-1 receptor-cannabinoid CB1 receptor heterodimerization results in both ligand-dependent and -independent coordinated alterations of receptor localization and function.
about
Cannabinoid-hypocretin cross-talk in the central nervous system: what we know so farAllostery at G protein-coupled receptor homo- and heteromers: uncharted pharmacological landscapesG-protein-coupled receptor heteromers: function and ligand pharmacologyPhysiology of the orexinergic/hypocretinergic system: a revisit in 2012OX1 and OX2 orexin/hypocretin receptor pharmacogeneticsMultiple roles for orexin/hypocretin in addictionThe action and mode of binding of thiazolidinedione ligands at free fatty acid receptor 1Cannabinoid receptor 1 signaling in cardiovascular regulating nuclei in the brainstem: A reviewA pivotal role for enhanced brainstem Orexin receptor 1 signaling in the central cannabinoid receptor 1-mediated pressor response in conscious ratsInternational Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CB₂Formation of mu-/kappa-opioid receptor heterodimer is sex-dependent and mediates female-specific opioid analgesiaFunctional characterization of G-protein-coupled receptors: a bioinformatics approach.Pharmacotherapeutic targeting of the endocannabinoid signaling system: drugs for obesity and the metabolic syndrome.Endocannabinoids, blood pressure and the human heart.Hepatitis C virus induces the cannabinoid receptor 1.Toward the Development of Bivalent Ligand Probes of Cannabinoid CB1 and Orexin OX1 Receptor Heterodimers.Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.Targeting CB2-GPR55 receptor heteromers modulates cancer cell signaling.The year in G protein-coupled receptor research.Cannabinoid CB1 receptor-interacting proteins: novel targets for central nervous system drug discovery?Endocannabinoid signalling: has it got rhythm?Physical and functional interaction between CB1 cannabinoid receptors and beta2-adrenoceptorsOrexin A induces GnRH gene expression and secretion from GT1-7 hypothalamic GnRH neurons.Psychopharmacology of the endocannabinoids: far beyond anandamide.Diencephalic and brainstem mechanisms in migraine.Multiple functions of endocannabinoid signaling in the brain.Dopamine D1-histamine H3 receptor heteromers provide a selective link to MAPK signaling in GABAergic neurons of the direct striatal pathway.Ghrelin-induced orexigenic effect in rats depends on the metabolic status and is counteracted by peripheral CB1 receptor antagonism.Evidence for an association between migraine and the hypocretin receptor 1 geneDiaryl urea analogues of SB-334867 as orexin-1 receptor antagonists.GPCR Heterodimerization in the Reproductive System: Functional Regulation and Implication for BiodiversityAT1R-CB₁R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II.Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaineDifferential modulation of brainstem phosphatidylinositol 3-kinase/Akt and extracellular signal-regulated kinase 1/2 signaling underlies WIN55,212-2 centrally mediated pressor response in conscious rats.Functional homomers and heteromers of dopamine D2L and D3 receptors co-exist at the cell surfaceBiological Significance of GPCR Heteromerization in the Neuro-Endocrine SystemCannabinoid receptor CB1 regulates STAT3 activity and its expression dictates the responsiveness to SR141716 treatment in human glioma patients' cellsThe cannabinoid receptor CB1 modulates the signaling properties of the lysophosphatidylinositol receptor GPR55.Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsyG Protein-coupled Receptor Biased Agonism.
P2860
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P2860
Orexin-1 receptor-cannabinoid CB1 receptor heterodimerization results in both ligand-dependent and -independent coordinated alterations of receptor localization and function.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Orexin-1 receptor-cannabinoid ...... tor localization and function.
@en
type
label
Orexin-1 receptor-cannabinoid ...... tor localization and function.
@en
prefLabel
Orexin-1 receptor-cannabinoid ...... tor localization and function.
@en
P2093
P2860
P921
P356
P1476
Orexin-1 receptor-cannabinoid ...... tor localization and function.
@en
P2093
Graeme Milligan
James Ellis
John D Pediani
Meritxell Canals
Sandra Milasta
P2860
P304
38812-38824
P356
10.1074/JBC.M602494200
P407
P577
2006-10-02T00:00:00Z