TMEM16F (Anoctamin 6), an anion channel of delayed Ca(2+) activation. - Wikidata - awgldk - TriplyDB

TMEM16F (Anoctamin 6), an anion channel of delayed Ca(2+) activation.

TMEM16F (Anoctamin 6), an anion channel of delayed Ca(2+) activation.

http://www.wikidata.org/entity/Q40227066

about

Anoctamin-6 controls bone mineralization by activating the calcium transporter NCX1 A Pore Idea: the ion conduction pathway of TMEM16/ANO proteins is composed partly of lipid Calmodulin regulation of TMEM16A and 16B Ca(2+)-activated chloride channels Calmodulin-dependent activation and inactivation of anoctamin calcium-gated chloride channels Acidic amino acids in the first intracellular loop contribute to voltage- and calcium- dependent gating of anoctamin1/TMEM16A.Anoctamin 6 differs from VRAC and VSOAC but is involved in apoptosis and supports volume regulation in the presence of Ca2+.Modulating Ca²⁺ signals: a common theme for TMEM16, Ist2, and TMC.Anoctamin 6 regulates C2C12 myoblast proliferation ANO1 (TMEM16A) in pancreatic ductal adenocarcinoma (PDAC)Molecular and functional significance of Ca(2+)-activated Cl(-) channels in pulmonary arterial smooth muscle.Identification of a lipid scrambling domain in ANO6/TMEM16F.Two helices in the third intracellular loop determine anoctamin 1 (TMEM16A) activation by calcium The ER/PM microdomain, PI(4,5)P₂ and the regulation of STIM1-Orai1 channel function.Independent activation of distinct pores in dimeric TMEM16A channels Regulatory Roles of Anoctamin-6 in Human Trabecular Meshwork Cells Ion channels and transporters in the development of drug resistance in cancer cells Functions of volume-sensitive and calcium-activated chloride channels.TMEM16 proteins: unknown structure and confusing functions.Ca2+-dependent phospholipid scrambling by a reconstituted TMEM16 ion channel.Effects of new-generation TMEM16A inhibitors on calcium-activated chloride currents in rabbit urethral interstitial cells of Cajal.Ca2+ signals, cell membrane disintegration, and activation of TMEM16F during necroptosis.Ion channels in regulated cell death.Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms.Selective serotonin reuptake inhibitors facilitate ANO6 (TMEM16F) current activation and phosphatidylserine exposure.Homodimeric anoctamin-1, but not homodimeric anoctamin-6, is activated by calcium increases mediated by the P2Y1 and P2X7 receptors.New Insights on the Regulation of Ca2+ -Activated Chloride Channel TMEM16A.Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR).Cl- channels in apoptosis.Anoctamin 6 Contributes to Cl- Secretion in Accessory Cholera Enterotoxin (Ace)-stimulated Diarrhea: AN ESSENTIAL ROLE FOR PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE (PIP2) SIGNALING IN CHOLERA.Cell-specific mechanisms of TMEM16A Ca2+-activated chloride channel in cancer.The role of TMEM16A (ANO1) and TMEM16F (ANO6) in cell migration Lipids and ions traverse the membrane by the same physical pathway in the nhTMEM16 scramblase.Phylogenetic, expression, and functional analyses of anoctamin homologs in Caenorhabditis elegans.Activation of the phospholipid scramblase TMEM16F by nanosecond pulsed electric fields (nsPEF) facilitates its diverse cytophysiological effects.CFTR supports cell death through ROS-dependent activation of TMEM16F (anoctamin 6).Gain of function of TMEM16E/ANO5 scrambling activity caused by a mutation associated with gnathodiaphyseal dysplasia.TMEM16E (GDD1) exhibits protein instability and distinct characteristics in chloride channel/pore forming ability.Cellular volume regulation by anoctamin 6: Ca²⁺, phospholipase A2 and osmosensing.Chloride Homeostasis in Neurons With Special Emphasis on the Olivocerebellar System: Differential Roles for Transporters and Channels.

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P2860

TMEM16F (Anoctamin 6), an anion channel of delayed Ca(2+) activation.

http://www.wikidata.org/entity/Q40227066

description

2013 nî lūn-bûn

@nan

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

TMEM16F (Anoctamin 6), an anion channel of delayed Ca(2+) activation.

@en

type

label

TMEM16F (Anoctamin 6), an anion channel of delayed Ca(2+) activation.

@en

prefLabel

TMEM16F (Anoctamin 6), an anion channel of delayed Ca(2+) activation.

@en

P1433

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P1433

The Journal of General Physiology

P1476

TMEM16F (Anoctamin 6), an anion channel of delayed Ca(2+) activation.

@en

P2093

Christian Ammitzbøll Juul

http://www.w3.org/2001/XMLSchema#string

Else K Hoffmann

http://www.w3.org/2001/XMLSchema#string

Erik Hviid Larsen

http://www.w3.org/2001/XMLSchema#string

Kristian A Poulsen

http://www.w3.org/2001/XMLSchema#string

Søren Grubb

http://www.w3.org/2001/XMLSchema#string

Tania Kyed

http://www.w3.org/2001/XMLSchema#string

Thomas K Klausen

http://www.w3.org/2001/XMLSchema#string

P2860

The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels

Anoctamin 6 is an essential component of the outwardly rectifying chloride channel

ANOs 3-7 in the anoctamin/Tmem16 Cl- channel family are intracellular proteins

Calcium-dependent phospholipid scrambling by TMEM16F

NGEP, a gene encoding a membrane protein detected only in prostate cancer and normal prostate

TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals

Characterization of the oligomeric structure of the Ca(2+)-activated Cl- channel Ano1/TMEM16A

Chloride channels as drug targets.

TMEM16A(a)/anoctamin-1 shares a homodimeric architecture with CLC chloride channels

Anoctamin/TMEM16 family members are Ca2+-activated Cl- channels

P304

585-600

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1085/JGP.201210861

http://www.w3.org/2001/XMLSchema#string

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

141

http://www.w3.org/2001/XMLSchema#string

P577

2013-05-01T00:00:00Z

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P5875

236581849

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P698

23630341

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P932

3639583

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