Mouse Cx50, a functional member of the connexin family of gap junction proteins, is the lens fiber protein MP70.
about
A missense mutation in the human connexin50 gene (GJA8) underlies autosomal dominant "zonular pulverulent" cataract, on chromosome 1qThe human lens intrinsic membrane protein MP70 (Cx50) gene: clonal analysis and chromosome mappingProperties of gap junction channels formed by Cx46 alone and in combination with Cx50.Quinine blocks specific gap junction channel subtypesFunctional role of the carboxyl terminal domain of human connexin 50 in gap junctional channelsLens connexins alpha3Cx46 and alpha8Cx50 interact with zonula occludens protein-1 (ZO-1)7-Ketocholesterol modulates intercellular communication through gap-junction in bovine lens epithelial cellsThe human lens fiber-cell intrinsic membrane protein MP19 gene: isolation and sequence analysisPurification and oligomeric state of the major lens fiber cell membrane proteinsGap junctions in the inner ear: comparison of distribution patterns in different vertebrates and assessement of connexin composition in mammalsDistinct permeation profiles of the connexin 30 and 43 hemichannelsConnexin 46 and connexin 50 in selenite cataractUpregulation and maintenance of gap junctional communication in lens cellsTransgenic overexpression of connexin50 induces cataracts.Decreased gap junctional communication in neurobiotin microinjected lens epithelial cells after taxol treatment.Microinjection of actin antibodies impaired gap junctional intercellular communication in lens epithelial cells in vitro.The cytoplasmic accumulations of the cataract-associated mutant, Connexin50P88S, are long-lived and form in the endoplasmic reticulum.Gap junctional coupling in lenses lacking alpha3 connexinRegulation of lens gap junctions by Transforming Growth Factor beta.Species-specific voltage-gating properties of connexin-45 junctions expressed in Xenopus oocytes.Xenopus connexin38 forms hemi-gap-junctional channels in the nonjunctional plasma membrane of Xenopus oocytes.Distinct behavior of connexin56 and connexin46 gap junctional channels can be predicted from the behavior of their hemi-gap-junctional channels.Different ionic selectivities for connexins 26 and 32 produce rectifying gap junction channelsCo-expression of lens fiber connexins modifies hemi-gap-junctional channel behavior.Exchange of gating properties between rat cx46 and chicken cx45.6.Gap junctions are selectively associated with interlocking ball-and-sockets but not protrusions in the lensMolecular cloning and functional characterization of chick lens fiber connexin 45.6.Functional analysis of selective interactions among rodent connexins.Wounding alters epidermal connexin expression and gap junction-mediated intercellular communicationMutation of the gap junction protein alpha 8 (GJA8) gene causes autosomal recessive cataract.Cataracts and microphthalmia caused by a Gja8 mutation in extracellular loop 2.Connexin 46 (cx46) gap junctions provide a pathway for the delivery of glutathione to the lens nucleusProperties of connexin 46 hemichannels in dissociated lens fiber cellsIdentification and functional analysis of GJA8 mutation in a Chinese family with autosomal dominant perinuclear cataracts.Different consequences of cataract-associated mutations at adjacent positions in the first extracellular boundary of connexin50Investigation of the reciprocal relationship between the expression of two gap junction connexin proteins, connexin46 and connexin43.Developmental genetics in ophthalmology.Another evidence for a D47N mutation in GJA8 associated with autosomal dominant congenital cataract.Cx50 requires an intact PDZ-binding motif and ZO-1 for the formation of functional intercellular channels.Functional characterization of a naturally occurring Cx50 truncation
P2860
Q24316327-E06C8DE8-4DA5-4492-84D4-F421A82A415BQ24324251-301292B4-D9A0-4B83-A055-7AABDB45A164Q24537393-AD857BE3-842E-46C1-B5C2-16A8A0B57A0AQ24555201-E0DB95AC-9BF0-4731-9B1F-7741AF1E2D71Q24654049-09413897-C4E4-4B31-B332-815CD9BD4B79Q24679811-4B3F23DF-2F76-4868-8867-9E1460C72FD4Q24792839-8C92D1A1-B086-4676-923E-2EDD0DC008D4Q28251036-30B9A0D3-2672-4FBE-B582-244D0D803A31Q28270888-56D3DF81-EFCB-4D5F-9F52-6308124FFB8FQ28508885-FAAF168F-D2DC-4381-9864-FEFA6489CB90Q28581350-45D5E412-DE12-4F08-ACCC-0B538D90C634Q28582167-255EF0B9-E7A9-49F8-ABAB-11A45EF01A7CQ28752600-0B42B143-F469-41FA-BECC-FF44D9E4E7B1Q30479349-D31D6C07-8656-4169-960C-4A8F46E76698Q31166370-812567F8-4947-4B9C-92A5-D504AE2B1DADQ33193980-E9933B1E-D7EF-4EA4-8895-73B340E29D8DQ33392090-FD23DFCC-F6C3-4F1B-9C77-6F9E9E1832E2Q33580006-D3000839-3DC3-4918-9BC2-683CFDE59C62Q33848751-6DBBC40E-78DD-4AC7-988F-BCE8761C55D9Q33907175-9D4C147B-FF29-4A90-AAC2-F7E75B0ECED0Q34040301-8520359A-B094-447E-8854-B4043116BFB4Q34129363-02981252-AF5C-4ED8-B279-6A0EB3208BB2Q34171884-BD25E8CA-224F-46AF-8504-245BC2D8885BQ34179809-EE7EF391-AF35-4ED4-8F74-2DFB3DC00081Q34187324-851F7167-63D9-4F79-90ED-F65B287C3FEBQ34366263-3F85BCAD-A521-489B-BC7F-CACC58B105B9Q34441564-651D66D8-729D-41B8-AD43-FD8677BC9D2FQ34448036-392E72AC-AFB0-4D1B-9AA0-2154A3C24204Q34452878-AEA057CB-E7CC-4409-95D7-D957AAB5BC8DQ34530828-E5EA10AE-1E61-4B98-8651-0E931442563DQ34541356-10DC73AF-AF71-4A58-A400-59B25900F11BQ34552658-AA616D9C-E3C6-48E4-91B4-0F03F3446AB3Q34645738-8551C39C-8727-4B4F-90C7-4A0CDC7ABE01Q34652632-1D131DDF-E724-4489-ACA7-1795C7D3944AQ34979286-344BF2BA-4419-40FD-A0B9-40CCBC7F5477Q35085210-6C5BAB3B-33C3-4179-89C9-1C40AD8514E5Q35093268-50EC5D45-2238-4BEC-81BE-1FBDA9CA2B6CQ35209179-A7DCBE33-71F1-4BB0-A4CB-63225B13A16FQ35579792-86894E3A-437C-44D6-90A5-1D35E101A768Q35607498-EE7A6DC3-1CE7-4BC7-9785-E2F6F878AE6B
P2860
Mouse Cx50, a functional member of the connexin family of gap junction proteins, is the lens fiber protein MP70.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Mouse Cx50, a functional membe ...... s the lens fiber protein MP70.
@en
type
label
Mouse Cx50, a functional membe ...... s the lens fiber protein MP70.
@en
prefLabel
Mouse Cx50, a functional membe ...... s the lens fiber protein MP70.
@en
P2093
P2860
P356
P1476
Mouse Cx50, a functional membe ...... s the lens fiber protein MP70.
@en
P2093
D A Goodenough
R Bruzzone
P2860
P304
P356
10.1091/MBC.3.7.711
P577
1992-07-01T00:00:00Z