Graded regulation of the Kv2.1 potassium channel by variable phosphorylation.
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Ca2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sitesShotgun proteomics in neuroscienceHyper-SUMOylation of the Kv7 potassium channel diminishes the M-current leading to seizures and sudden death.Suppression of a pro-apoptotic K+ channel as a mechanism for hepatitis C virus persistencePost-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmiasDeletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability.Proteomic analyses of native brain K(V)4.2 channel complexesFormation of heteromeric Kv2 channels in mammalian brain neuronsRearrangements in the relative orientation of cytoplasmic domains induced by a membrane-anchored protein mediate modulations in Kv channel gatingCdk-mediated phosphorylation of the Kvβ2 auxiliary subunit regulates Kv1 channel axonal targetingThe Kv2.1 K+ channel targets to the axon initial segment of hippocampal and cortical neurons in culture and in situ.Analysis of protein phosphorylation in nerve terminal reveals extensive changes in active zone proteins upon exocytosisProteome-wide survey of phosphorylation patterns affected by nuclear DNA polymorphisms in Arabidopsis thalianaSingle particle image reconstruction of the human recombinant Kv2.1 channel.15N-labeled brain enables quantification of proteome and phosphoproteome in cultured primary neurons.Analysis and functional implications of phosphorylation of neuronal voltage-gated potassium channels.Nitric oxide is an activity-dependent regulator of target neuron intrinsic excitabilityRedistribution of Kv2.1 ion channels on spinal motoneurons following peripheral nerve injuryMultisite phosphorylation of the NDC80 complex gradually tunes its microtubule-binding affinity.Mass spectrometric analysis reveals a functionally important PKA phosphorylation site in a Kir3 channel subunitTowards a general theory of neural computation based on prediction by single neurons.Light-dependent phosphorylation of the drosophila transient receptor potential ion channel.Altered Kv2.1 functioning promotes increased excitability in hippocampal neurons of an Alzheimer's disease mouse model.Zn2+ regulates Kv2.1 voltage-dependent gating and localization following ischemia.Mechanisms of Kv2.1 channel inhibition by celecoxib--modification of gating and channel blockSystematic Synergy of Glucose and GLP-1 to Stimulate Insulin Secretion Revealed by Quantitative Phosphoproteomics.Oxidation of KCNB1 K(+) channels in central nervous system and beyondMultisite phosphorylation of voltage-gated sodium channel alpha subunits from rat brainReactive oxygen species scavengers improve voltage-gated K(+) channel function in pulmonary arteries of newborn pigs with progressive hypoxia-induced pulmonary hypertension.Downregulation of dendritic HCN channel gating in epilepsy is mediated by altered phosphorylation signaling.Localization-dependent activity of the Kv2.1 delayed-rectifier K+ channel.Cell type-specific spatial and functional coupling between mammalian brain Kv2.1 K+ channels and ryanodine receptors.Reduction in voltage-gated K+ channel activity in primary sensory neurons in painful diabetic neuropathy: role of brain-derived neurotrophic factorPhosphorylation in protein-protein binding: effect on stability and function.Swimming against the tide: investigations of the C-bouton synapse.Benefits and pitfalls of secondary antibodies: why choosing the right secondary is of primary importanceGraded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation.Voltage-gated potassium channels at the crossroads of neuronal function, ischemic tolerance, and neurodegeneration.Mining recent brain proteomic databases for ion channel phosphosite nuggets.Phosphorylated hMSH6: DNA mismatch versus DNA damage recognition.
P2860
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P2860
Graded regulation of the Kv2.1 potassium channel by variable phosphorylation.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Graded regulation of the Kv2.1 potassium channel by variable phosphorylation.
@en
type
label
Graded regulation of the Kv2.1 potassium channel by variable phosphorylation.
@en
prefLabel
Graded regulation of the Kv2.1 potassium channel by variable phosphorylation.
@en
P2093
P356
P1433
P1476
Graded regulation of the Kv2.1 potassium channel by variable phosphorylation
@en
P2093
Hiroaki Misonou
James S Trimmer
Kang-Sik Park
P304
P356
10.1126/SCIENCE.1124254
P407
P577
2006-08-01T00:00:00Z