Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis.
about
Regulation of p63 isoforms by snail and slug transcription factors in human squamous cell carcinomaTrop2 and its overexpression in cancers: regulation and clinical/therapeutic implicationsdeltaNp63 has a role in maintaining epithelial integrity in airway epitheliumΔNp63α and microRNAs: leveraging the epithelial-mesenchymal transitionΔNp63 is an ectodermal gatekeeper of epidermal morphogenesisSPATA18, a spermatogenesis-associated gene, is a novel transcriptional target of p53 and p63Discovering biological connections between experimental conditions based on common patterns of differential gene expressionIdentification of markers of taxane sensitivity using proteomic and genomic analyses of breast tumors from patients receiving neoadjuvant paclitaxel and radiation.Novel in vivo targets of DeltaNp63 in keratinocytes identified by a modified chromatin immunoprecipitation approachReciprocal regulation of p63 by C/EBP delta in human keratinocytes.Ets1 induces dysplastic changes when expressed in terminally-differentiating squamous epidermal cellsTranscriptional network of p63 in human keratinocytes.ΔNp63 isoform-mediated β-defensin family up-regulation is associated with (lymph)angiogenesis and poor prognosis in patients with squamous cell carcinoma.ΔNp63α is a common inhibitory target in oncogenic PI3K/Ras/Her2-induced cell motility and tumor metastasis.C/EBPδ gene targets in human keratinocytes.Transcription factor p63 regulates key genes and wound repair in human airway epithelial basal cellsThe human papillomavirus E6 oncogene represses a cell adhesion pathway and disrupts focal adhesion through degradation of TAp63β upon transformationDeltaNp63alpha-mediated induction of epidermal growth factor receptor promotes pancreatic cancer cell growth and chemoresistancep63 and p73, the ancestors of p53.TAp63 is important for cardiac differentiation of embryonic stem cells and heart development.YAP dysregulation by phosphorylation or ΔNp63-mediated gene repression promotes proliferation, survival and migration in head and neck cancer subsets.Novel p63 target genes involved in paracrine signaling and keratinocyte differentiation.Induction of ΔNp63 by the newly identified keratinocyte-specific transforming growth factor β Signaling Pathway with Smad2 and IκB Kinase α in squamous cell carcinoma.Molecular subtypes in head and neck cancer exhibit distinct patterns of chromosomal gain and loss of canonical cancer genes.New plays in the p53 theater.ADAM9 up-regulates N-cadherin via miR-218 suppression in lung adenocarcinoma cellsp63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53.p53 Family: Role of Protein Isoforms in Human Cancer.Pathway Regulation of p63, a Director of Epithelial Cell Fatep63 regulates human keratinocyte proliferation via MYC-regulated gene network and differentiation commitment through cell adhesion-related gene network.Cancer RNA-Seq Nexus: a database of phenotype-specific transcriptome profiling in cancer cellsΔNp63α Transcriptionally Regulates the Expression of CTEN That Is Associated with Prostate Cell Adhesion.Targeting IL13Ralpha2 activates STAT6-TP63 pathway to suppress breast cancer lung metastasisA new E6/P63 pathway, together with a strong E7/E2F mitotic pathway, modulates the transcriptome in cervical cancer cellsA new hypothesis for the cancer mechanism.ΔNp63α expression induces loss of cell adhesion in triple-negative breast cancer cells.ΔNp63α activates CD82 metastasis suppressor to inhibit cancer cell invasion.MinePath: Mining for Phenotype Differential Sub-paths in Molecular Pathways.Role of p63 in Development, Tumorigenesis and Cancer Progression1α, 25-Dihydroxyvitamin D₃ and the vitamin D receptor regulates ΔNp63α levels and keratinocyte proliferation.
P2860
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P2860
Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Loss of p63 leads to increased ...... ed in invasion and metastasis.
@en
type
label
Loss of p63 leads to increased ...... ed in invasion and metastasis.
@en
prefLabel
Loss of p63 leads to increased ...... ed in invasion and metastasis.
@en
P1433
P1476
Loss of p63 leads to increased ...... ed in invasion and metastasis.
@en
P2093
Kimberly A Brown
Luo Jia Tang
P304
P356
10.1158/0008-5472.CAN-06-2020
P407
P577
2006-08-01T00:00:00Z