Hyaluronan and the interaction between CD44 and epidermal growth factor receptor in oncogenic signaling and chemotherapy resistance in head and neck cancer.
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Hyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates beta-catenin signaling and NFkappaB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance in breast tumor cellsCD44 variant isoforms in head and neck squamous cell carcinoma progressionInteractions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and CancerCD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating CellsInteraction of low molecular weight hyaluronan with CD44 and toll-like receptors promotes the actin filament-associated protein 110-actin binding and MyD88-NFκB signaling leading to proinflammatory cytokine/chemokine production and breast tumor invaHigh expression of Lewis y antigen and CD44 is correlated with resistance to chemotherapy in epithelial ovarian cancersCD147, CD44, and the epidermal growth factor receptor (EGFR) signaling pathway cooperate to regulate breast epithelial cell invasiveness.Abrogating drug resistance in malignant peripheral nerve sheath tumors by disrupting hyaluronan-CD44 interactions with small hyaluronan oligosaccharides.The Extracellular Matrix in Epithelial Ovarian Cancer - A Piece of a Puzzle.Normal and malignant epithelial cells with stem-like properties have an extended G2 cell cycle phase that is associated with apoptotic resistanceMore than markers: biological significance of cancer stem cell-defining molecules.Reduction of hyaluronan-CD44-mediated growth, migration, and cisplatin resistance in head and neck cancer due to inhibition of Rho kinase and PI-3 kinase signaling.Transactivation of the receptor-tyrosine kinase ephrin receptor A2 is required for the low molecular weight hyaluronan-mediated angiogenesis that is implicated in tumor progression.Transforming growth factor-β1 (TGF-β1)-stimulated fibroblast to myofibroblast differentiation is mediated by hyaluronan (HA)-facilitated epidermal growth factor receptor (EGFR) and CD44 co-localization in lipid rafts.MicroRNA-7 inhibition rescues age-associated loss of epidermal growth factor receptor and hyaluronan-dependent differentiation in fibroblasts.CD44 staining of cancer stem-like cells is influenced by down-regulation of CD44 variant isoforms and up-regulation of the standard CD44 isoform in the population of cells that have undergone epithelial-to-mesenchymal transition.Inhibition of oesophageal squamous cell carcinoma progression by in vivo targeting of hyaluronan synthesis.Chemotherapy-induced hyaluronan production: a novel chemoresistance mechanism in ovarian cancer.Survivin is a novel target of CD44-promoted breast tumor invasionConcise Review: Targeting Cancer Stem Cells Using Immunologic ApproachesTumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells.Decreased expression of hyaluronan synthase 1 and 2 associates with poor prognosis in cutaneous melanoma.Expression of ALDH1A1 and CD44 in primary head and neck squamous cell carcinoma and their value for carcinogenesis, tumor progression and cancer stem cell identification.CD44 interacts with EGFR and promotes head and neck squamous cell carcinoma initiation and progression.Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells.Hyaluronan: a constitutive regulator of chemoresistance and malignancy in cancer cells.Hyaluronan, CD44 and Emmprin: partners in cancer cell chemoresistance.Evaluation of EGFR as a prognostic and diagnostic marker for head and neck squamous cell carcinoma patients.Epithelial stem cells and malignancy.The 'sweet' and 'bitter' involvement of glycosaminoglycans in lung diseases: pharmacotherapeutic relevance.Hyaluronan-CD44 interaction with protein kinase C(epsilon) promotes oncogenic signaling by the stem cell marker Nanog and the Production of microRNA-21, leading to down-regulation of the tumor suppressor protein PDCD4, anti-apoptosis, and chemotheraNovel dual cyclooxygenase and lipoxygenase inhibitors targeting hyaluronan-CD44v6 pathway and inducing cytotoxicity in colon cancer cells.Link protein hyaluronan-binding motif abrogates CD44-hyaluronan-mediated leukemia-liver cell adhesion.Antibodies targeting cancer stem cells: a new paradigm in immunotherapy?CD44: A Multifunctional Cell Surface Adhesion Receptor Is a Regulator of Progression and Metastasis of Cancer Cells.Hyaluronan synthase 3 mediated oncogenic action through forming inter-regulation loop with tumor necrosis factor alpha in oral cancer.Role of hyaluronan-mediated CD44 signaling in head and neck squamous cell carcinoma progression and chemoresistance.The potential of CD44 as a diagnostic and prognostic tool in oral cancer.Understanding the colon cancer stem cells and perspectives on treatment.Hyaluronan in cancer - from the naked mole rat to nanoparticle therapy.
P2860
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P2860
Hyaluronan and the interaction between CD44 and epidermal growth factor receptor in oncogenic signaling and chemotherapy resistance in head and neck cancer.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Hyaluronan and the interaction ...... tance in head and neck cancer.
@en
type
label
Hyaluronan and the interaction ...... tance in head and neck cancer.
@en
prefLabel
Hyaluronan and the interaction ...... tance in head and neck cancer.
@en
P1433
P1476
Hyaluronan and the interaction ...... tance in head and neck cancer.
@en
P2093
Lilly Y W Bourguignon
Steven J Wang
P304
P356
10.1001/ARCHOTOL.132.7.771
P577
2006-07-01T00:00:00Z