Oxidative stress by ascorbate/menadione association kills K562 human chronic myelogenous leukaemia cells and inhibits its tumour growth in nude mice.
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Redox-directed cancer therapeutics: molecular mechanisms and opportunitiesAntimelanoma activity of the redox dye DCPIP (2,6-dichlorophenolindophenol) is antagonized by NQO1Increasing Superoxide Production and the Labile Iron Pool in Tumor Cells may Sensitize Them to Extracellular AscorbateInduction of erythroid differentiation in human erythroleukemia cells by depletion of malic enzyme 2Knockdown of malic enzyme 2 suppresses lung tumor growth, induces differentiation and impacts PI3K/AKT signaling.Citrate Suppresses Tumor Growth in Multiple Models through Inhibition of Glycolysis, the Tricarboxylic Acid Cycle and the IGF-1R Pathway.Nucleolar changes and fibrillarin redistribution following apatone treatment of human bladder carcinoma cells.Metal-independent reduction of hydrogen peroxide by semiquinonesCellular phenotype-dependent and -independent effects of vitamin C on the renewal and gene expression of mouse embryonic fibroblastsCurrent limitations of murine models in oncology for ascorbate research.Phase I clinical trial of i.v. ascorbic acid in advanced malignancy.The Combination of Vitamin K3 and Vitamin C Has Synergic Activity against Forms of Trypanosoma cruzi through a Redox Imbalance Process.The naphthoquinones, vitamin K3 and its structural analogue plumbagin, are substrates of the multidrug resistance linked ATP binding cassette drug transporter ABCG2Ascorbic acid: chemistry, biology and the treatment of cancer.Synthesis and Evaluation of Folate-Conjugated Phenanthraquinones for Tumor-Targeted Oxidative Chemotherapy.A combination of two antioxidants (an SOD mimic and ascorbate) produces a pro-oxidative effect forcing Escherichia coli to adapt via induction of oxyR regulon.Molecular mechanisms of pharmacological doses of ascorbate on cancer cells.Proteomic analysis of the vitamin C effect on the doxorubicin cytotoxicity in the MCF-7 breast cancer cell line.Redirecting apoptosis to aponecrosis induces selective cytotoxicity to pancreatic cancer cells through increased ROS, decline in ATP levels, and VDAC.Mefloquine interferes with glycolysis in schistosomula of Schistosoma mansoni via inhibition of enolase.Aminopyrimidoisoquinolinequinone (APIQ) redox cycling is potentiated by ascorbate and induces oxidative stress leading to necrotic-like cancer cell death.Cell damage and death by autoschizis in human bladder (RT4) carcinoma cells resulting from treatment with ascorbate and menadione.Ascorbate/menadione-induced oxidative stress kills cancer cells that express normal or mutated forms of the oncogenic protein Bcr-Abl. An in vitro and in vivo mechanistic study.Losing and finding a way at C: new promise for pharmacologic ascorbate in cancer treatment.2-Bromo-1,4-naphthoquinone: a potentially improved substitute of menadione in Apatone™ therapy.Mega-dose vitamin C as therapy for human cancer?Cisplatin- and dietary ascorbic acid-mediated changes in the mitochondria of Dalton's lymphoma-bearing mice.High-dose ascorbic acid induces carcinostatic effects through hydrogen peroxide and superoxide anion radical generation-induced cell death and growth arrest in human tongue carcinoma cells.Catalase down-regulation in cancer cells exposed to arsenic trioxide is involved in their increased sensitivity to a pro-oxidant treatment.β-carotene treatment alters the cellular death process in oxidative stress-induced K562 cells.
P2860
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P2860
Oxidative stress by ascorbate/menadione association kills K562 human chronic myelogenous leukaemia cells and inhibits its tumour growth in nude mice.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Oxidative stress by ascorbate/ ...... ts tumour growth in nude mice.
@en
type
label
Oxidative stress by ascorbate/ ...... ts tumour growth in nude mice.
@en
prefLabel
Oxidative stress by ascorbate/ ...... ts tumour growth in nude mice.
@en
P2093
P1476
Oxidative stress by ascorbate/ ...... its tumour growth in nude mice
@en
P2093
Aurélie Tison
Henryk S Taper
Julien Verrax
Pedro Buc Calderon
P304
P356
10.1016/J.BCP.2006.05.025
P407
P577
2006-07-07T00:00:00Z