Self-association of the transmembrane domain of RET underlies oncogenic activation by MEN2A mutations.
about
Mutation-introduced dimerization of receptor tyrosine kinases: from protein structure aberrations to carcinogenesis.Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia.Normal activation of discoidin domain receptor 1 mutants with disulfide cross-links, insertions, or deletions in the extracellular juxtamembrane region: mechanistic implicationsOncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia.Structure and physiology of the RET receptor tyrosine kinase.Neurotrophic factor receptor RET: structure, cell biology, and inherited diseases.Single-spanning transmembrane domains in cell growth and cell-cell interactions: More than meets the eye?The Hirschsprung's-multiple endocrine neoplasia connection.Central role of RET in thyroid cancer.Exon Skipping in the RET Gene Encodes Novel Isoforms That Differentially Regulate RET Protein Signal Transduction.Protein-tyrosine phosphatase SHP2 contributes to GDNF neurotrophic activity through direct binding to phospho-Tyr687 in the RET receptor tyrosine kinase.Filopodia formation driven by membrane glycoprotein M6a depends on the interaction of its transmembrane domains.Discovery and functional characterization of a germline, CSF2RB-activating mutation in leukemia.Screening for transmembrane association in divisome proteins using TOXGREEN, a high-throughput variant of the TOXCAT assayPlot protein: visualization of mutations.Next-generation sequencing analysis of receptor-type tyrosine kinase genes in surgically resected colon cancer: identification of gain-of-function mutations in the RET proto-oncogene.Identification and characterization of two novel germline RET variants associated with medullary thyroid carcinoma.
P2860
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P2860
Self-association of the transmembrane domain of RET underlies oncogenic activation by MEN2A mutations.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Self-association of the transm ...... activation by MEN2A mutations.
@en
type
label
Self-association of the transm ...... activation by MEN2A mutations.
@en
prefLabel
Self-association of the transm ...... activation by MEN2A mutations.
@en
P2093
P2860
P356
P1433
P1476
Self-association of the transm ...... activation by MEN2A mutations.
@en
P2093
Abrescia C
Kurokawa K
Perrinjaquet M
P2860
P2888
P304
P356
10.1038/SJ.ONC.1209698
P407
P577
2006-05-29T00:00:00Z
P5875
P6179
1027197761