Conditionally replicating adenoviruses kill tumor cells via a basic apoptotic machinery-independent mechanism that resembles necrosis-like programmed cell death.
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Adenoviral delivery of pan-caspase inhibitor p35 enhances bystander killing by P450 gene-directed enzyme prodrug therapy using cyclophosphamide+Physical interventions to interrupt or reduce the spread of respiratory virusesPhysical interventions to interrupt or reduce the spread of respiratory virusesGoing viral: a review of replication-selective oncolytic adenovirusesAdenoviral vectors for prodrug activation-based gene therapy for cancerOncolytic viruses as anticancer vaccinesGenetic identification of adenovirus type 5 genes that influence viral spread.Human adenovirus type 5 induces cell lysis through autophagy and autophagy-triggered caspase activityEliminating established tumor in nu/nu nude mice by a tumor necrosis factor-alpha-related apoptosis-inducing ligand-armed oncolytic adenovirus.HCCS1-armed, quadruple-regulated oncolytic adenovirus specific for liver cancer as a cancer targeting gene-viro-therapy strategy.The HDAC Inhibitors Scriptaid and LBH589 Combined with the Oncolytic Virus Delta24-RGD Exert Enhanced Anti-Tumor Efficacy in Patient-Derived Glioblastoma CellsOncolytic Group B Adenovirus Enadenotucirev Mediates Non-apoptotic Cell Death with Membrane Disruption and Release of Inflammatory Mediators.New advance in caspase-independent programmed cell death and its potential in cancer therapyOncolytic adenoviral mutants induce a novel mode of programmed cell death in ovarian cancerHuman telomerase reverse transcriptase promoter-driven oncolytic adenovirus with E1B-19 kDa and E1B-55 kDa gene deletionsOncolytic adenoviral gene therapy in ovarian cancer: why we are not wasting our time.Oncolytic adenoviral vectors which employ the survivin promoter induce glioma oncolysis via a process of beclin-dependent autophagy.Oncolytic virotherapy with modified adenoviruses and novel therapeutic targets.Changing faces in virology: the dutch shift from oncogenic to oncolytic viruses.In vitro screening of clinical drugs identifies sensitizers of oncolytic viral therapy in glioblastoma stem-like cells.The oncolytic adenovirus Δ24-RGD in combination with cisplatin exerts a potent anti-osteosarcoma activity.Cancer targeting Gene-Viro-Therapy of liver carcinoma by dual-regulated oncolytic adenovirus armed with TRAIL gene.Dual E1A oncolytic adenovirus: targeting tumor heterogeneity with two independent cancer-specific promoter elements, DF3/MUC1 and hTERT.Benzo(a)pyrene induces p73 mRNA expression and necrosis in human lung adenocarcinoma H1299 cells.The viral tropism of two distinct oncolytic viruses, reovirus and myxoma virus, is modulated by cellular tumor suppressor gene status.Improved potency and selectivity of an oncolytic E1ACR2 and E1B19K deleted adenoviral mutant in prostate and pancreatic cancers.Oncolytic adenoviral mutants with E1B19K gene deletions enhance gemcitabine-induced apoptosis in pancreatic carcinoma cells and anti-tumor efficacy in vivo.Potent antitumor efficacy of XAF1 delivered by conditionally replicative adenovirus vector via caspase-independent apoptosis.Development of an Oncolytic Adenovirus with Enhanced Spread Ability through Repeated UV Irradiation and Cancer SelectionThe E1B19K-deleted oncolytic adenovirus mutant AdΔ19K sensitizes pancreatic cancer cells to drug-induced DNA-damage by down-regulating Claspin and Mre11Characterization of the recombinant adenovirus vector AdYB-1: implications for oncolytic vector development.Synergistic and Selective Cancer Cell Killing Mediated by the Oncolytic Adenoviral Mutant AdΔΔ and Dietary Phytochemicals in Prostate Cancer Models.Meganuclease-mediated virus self-cleavage facilitates tumor-specific virus replication.Human dendritic cells efficiently phagocytose adenoviral oncolysate but require additional stimulation to mature.Genetically engineered oncolytic adenovirus induces autophagic cell death through an E2F1-microRNA-7-epidermal growth factor receptor axis.Paclitaxel and vincristine potentiate adenoviral oncolysis that is associated with cell cycle and apoptosis modulation, whereas they differentially affect the viral life cycle in non-small-cell lung cancer cells.
P2860
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P2860
Conditionally replicating adenoviruses kill tumor cells via a basic apoptotic machinery-independent mechanism that resembles necrosis-like programmed cell death.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Conditionally replicating aden ...... is-like programmed cell death.
@en
type
label
Conditionally replicating aden ...... is-like programmed cell death.
@en
prefLabel
Conditionally replicating aden ...... is-like programmed cell death.
@en
P2093
P2860
P1433
P1476
Conditionally replicating aden ...... is-like programmed cell death.
@en
P2093
Frank A E Kruyt
Ida van der Meulen-Muileman
Mohamed A I Abou El Hassan
Saman Abbas
P2860
P304
12243-12251
P356
10.1128/JVI.78.22.12243-12251.2004
P407
P577
2004-11-01T00:00:00Z