Unmasking the redundancy between Cdk1 and Cdk2 at G2 phase in human cancer cell lines.
about
Chemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cellsCdk2 is required for p53-independent G2/M checkpoint control.Cell cycle proliferation decisions: the impact of single cell analyses.CDK1 plays an important role in the maintenance of pluripotency and genomic stability in human pluripotent stem cellsRole of Cdk1 in the p53-independent abrogation of the postmitotic checkpoint by human papillomavirus E6SP600125 suppresses Cdk1 and induces endoreplication directly from G2 phase, independent of JNK inhibition.Putative multifunctional signature of lung metastases in dedifferentiated chondrosarcoma.Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration.Role of Cdk1 in DNA damage-induced G1 checkpoint abrogation by the human papillomavirus E7 oncogene.Distinct activation pathways confer cyclin-binding specificity on Cdk1 and Cdk2 in human cellsCyclin-dependent kinases (cdks) and the DNA damage response: rationale for cdk inhibitor-chemotherapy combinations as an anticancer strategy for solid tumors.The roles and therapeutic potential of cyclin-dependent kinases (CDKs) in sarcoma.Discovery of Dinaciclib (SCH 727965): A Potent and Selective Inhibitor of Cyclin-Dependent Kinases.Easy Identification of Residues Involved on Structural Differences Between Nonphosphorylated and Phosphorylated CDK2Cyclin A Complexes Using Two-Dimensional Networks.Cdk1 participates in BRCA1-dependent S phase checkpoint control in response to DNA damage.Putting one step before the other: distinct activation pathways for Cdk1 and Cdk2 bring order to the mammalian cell cycleRescue of a human cell line from endogenous Cdk1 depletion by Cdk1 lacking inhibitory phosphorylation sites.Role of Cdc6 in re-replication in cells expressing human papillomavirus E7 oncogenePreventing DNA over-replication: a Cdk perspective.Molecular profiling and combinatorial activity of CCT068127: a potent CDK2 and CDK9 inhibitor.SDF-1/CXCR4 signaling up-regulates survivin to regulate human sacral chondrosarcoma cell cycle and epithelial-mesenchymal transition via ERK and PI3K/AKT pathway.Structural insights into the functional diversity of the CDK-cyclin family
P2860
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P2860
Unmasking the redundancy between Cdk1 and Cdk2 at G2 phase in human cancer cell lines.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Unmasking the redundancy between Cdk1 and Cdk2 at G2 phase in human cancer cell lines.
@en
type
label
Unmasking the redundancy between Cdk1 and Cdk2 at G2 phase in human cancer cell lines.
@en
prefLabel
Unmasking the redundancy between Cdk1 and Cdk2 at G2 phase in human cancer cell lines.
@en
P2093
P356
P1433
P1476
Unmasking the redundancy between Cdk1 and Cdk2 at G2 phase in human cancer cell lines.
@en
P2093
Lawrence L'Italien
Loren Russell
Marcel Tanudji
Xiao Min Schebye
P304
P356
10.4161/CC.5.9.2721
P577
2006-05-01T00:00:00Z