Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease.
about
Mendelian randomization in cardiometabolic disease: challenges in evaluating causality.The Role of Emerging Risk Factors in Cardiovascular OutcomesPhysiological and therapeutic regulation of PCSK9 activity in cardiovascular disease.Advances in dyslipidemia management for prevention of atherosclerosis: PCSK9 monoclonal antibody therapy and beyondStatin-ezetimibe versus statin lipid-lowering therapy in patients with acute coronary syndromes undergoing percutaneous coronary interventionRecent advances in preventing stroke recurrence.Heterozygous Familial Hypercholesterolemia With APOE Haplotype: A Prospective Harbinger of a Catastrophic Cardiovascular Event.Brazilian guidelines on prevention of cardiovascular disease in patients with diabetes: a position statement from the Brazilian Diabetes Society (SBD), the Brazilian Cardiology Society (SBC) and the Brazilian Endocrinology and Metabolism Society (SBNew data on familial hypercholesterolaemia and acute coronary syndromes: The promise of PCSK9 monoclonal antibodies in the light of recent clinical trials.Atherogenic Lipoprotein Determinants of Cardiovascular Disease and Residual Risk Among Individuals With Low Low-Density Lipoprotein Cholesterol.Pharmacokinetics, Pharmacodynamics of Bococizumab, a monoclonal antibody to PCSK9, After Single Subcutaneous Injection at 3 Sites [NCT 02043301].Patient Characteristics and Real-World Treatment Patterns Among Early Users of PCSK9 Inhibitors.Cost-effectiveness of Evolocumab Therapy for Reducing Cardiovascular Events in Patients With Atherosclerotic Cardiovascular Disease.Evolocumab for the treatment of hypercholesterolemia.The Role of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in Cardiovascular Homeostasis: A Non-Systematic Literature Review.Cholesterol Management in the Era of PCSK9 Inhibitors.Addressing the challenge of high-priced prescription drugs in the era of precision medicine: A systematic review of drug life cycles, therapeutic drug markets and regulatory frameworks.Lipid Lowering Therapy and Circulating PCSK9 Concentration.Simulation of Lipid-Lowering Therapy Intensification in a Population With Atherosclerotic Cardiovascular Disease.Navigating the Future of Cardiovascular Drug Development-Leveraging Novel Approaches to Drive Innovation and Drug Discovery: Summary of Findings from the Novel Cardiovascular Therapeutics Conference.Anti-PCSK9 antibodies for hypercholesterolaemia: Overview of clinical data and implications for primary care.Therapeutic targeting in nanomedicine: the future lies in recombinant antibodies.Efficacy and safety of proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors, alirocumab and evolocumab, a post-commercialization study.Emerging biologic therapies for hypercholesterolaemia.Inhibition of PCSK9 does not improve lipopolysaccharide-induced mortality in mice.PCSK9 and infection: A potentially useful or dangerous association?Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease.Can LDL cholesterol be too low? Possible risks of extremely low levels.Vascular inflammation and low-density lipoproteins: is cholesterol the link? A lesson from the clinical trials.Targeting low-density lipoprotein cholesterol with PCSK9 inhibitors.MicroRNAs: New Therapeutic Targets for Familial Hypercholesterolemia?Treatment of Dyslipidemia Using CRISPR/Cas9 Genome Editing.Translating Guidelines Into Practice: Interpreting the 2016 ACC Expert Consensus Decision Pathway on the Role of Non-Statin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk.PCSK9 Inhibitors: Treating the Right Patients in Daily Practice.Practical Considerations for the Use of Subcutaneous Treatment in the Management of Dyslipidaemia.Hepatitis C virus and proprotein convertase subtilisin/kexin type 9: a detrimental interaction to increase viral infectivity and disrupt lipid metabolism.PCSK9 in context: A contemporary review of an important biological target for the prevention and treatment of atherosclerotic cardiovascular disease.Clinical utility of evolocumab in the management of hyperlipidemia: patient selection and follow-up.Potential Role of Thyroid Receptor β Agonists in the Treatment of Hyperlipidemia.Cardiovascular risk and dyslipidemia among persons living with HIV: a review.
P2860
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P2860
Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease.
@en
type
label
Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease.
@en
prefLabel
Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease.
@en
P2093
P356
P1476
Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease.
@en
P2093
Anthony C Keech
FOURIER Steering Committee and Investigators
Julia F Kuder
Marc S Sabatine
Narimon Honarpour
Peter S Sever
Sabina A Murphy
Scott M Wasserman
Stephen D Wiviott
P304
P356
10.1056/NEJMOA1615664
P407
P577
2017-03-17T00:00:00Z