about
Cancer as an evolutionary and ecological processOptimal treatment and stochastic modeling of heterogeneous tumorsComputational Cancer Biology: An Evolutionary PerspectiveEvolutionary rescue: linking theory for conservation and medicineCancer evolution: mathematical models and computational inferenceEvolution of resistance to targeted anti-cancer therapies during continuous and pulsed administration strategiesFitness conferred by BCR-ABL kinase domain mutations determines the risk of pre-existing resistance in chronic myeloid leukemiaStochastic Tunneling of Two Mutations in a Population of Cancer CellsDrug resistance missense mutations in cancer are subject to evolutionary constraintsEvolution of pre-existing versus acquired resistance to platinum drugs and PARP inhibitors in BRCA-associated cancersSpatial heterogeneity in drug concentrations can facilitate the emergence of resistance to cancer therapyDose-Dependent Mutation Rates Determine Optimum Erlotinib Dosing Strategies for EGFR Mutant Non-Small Cell Lung Cancer PatientsPOPULATION GENETICS OF NEUTRAL MUTATIONS IN EXPONENTIALLY GROWING CANCER CELL POPULATIONSThe molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancersTranslating neoadjuvant therapy into survival benefits: one size does not fit all.Rational design of non-resistant targeted cancer therapiesEvolution of acquired resistance to anti-cancer therapy.MICU1 drives glycolysis and chemoresistance in ovarian cancer.Comparable ecological dynamics underlie early cancer invasion and species dispersal, involving self-organizing processes.Role of symmetric and asymmetric division of stem cells in developing drug resistance.Accumulation of driver and passenger mutations during tumor progression.Timing and heterogeneity of mutations associated with drug resistance in metastatic cancersA Bmi1-miRNAs cross-talk modulates chemotherapy response to 5-fluorouracil in breast cancer cellsAn exposure to the oxidized DNA enhances both instability of genome and survival in cancer cells.MicroRNA-mediated drug resistance in breast cancer.Down-regulated miR-331-5p and miR-27a are associated with chemotherapy resistance and relapse in leukaemia.Age-abundance relationships for neutral communities.Quantifying Clonal and Subclonal Passenger Mutations in Cancer Evolution.Dynamics of preventive vs post-diagnostic cancer control using low-impact measures.Increased expression of P-glycoprotein and doxorubicin chemoresistance of metastatic breast cancer is regulated by miR-298.The evolution of tumor metastasis during clonal expansion with alterations in metastasis driver genesA branching process model of ovarian cancer.Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling.Applying ecological and evolutionary theory to cancer: a long and winding road.Mathematical models of targeted cancer therapy.Impact of deleterious passenger mutations on cancer progression.Large population solution of the stochastic Luria-Delbruck evolution model.Feedback Regulation in a Cancer Stem Cell Model can Cause an Allee Effect.TrAp: a tree approach for fingerprinting subclonal tumor composition.Evolution of cell motility in an individual-based model of tumour growth.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Evolution of resistance during clonal expansion.
@en
type
label
Evolution of resistance during clonal expansion.
@en
prefLabel
Evolution of resistance during clonal expansion.
@en
P2093
P2860
P1433
P1476
Evolution of resistance during clonal expansion.
@en
P2093
Franziska Michor
Martin A Nowak
P2860
P304
P356
10.1534/GENETICS.105.049791
P407
P577
2006-04-01T00:00:00Z