Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression.
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Regulation of the embryonic morphogen Nodal by Notch4 facilitates manifestation of the aggressive melanoma phenotypeTargeting Notch to overcome radiation resistanceThe cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells?Targeting the Notch signaling pathway in cancer therapeuticsSignaling cross-talk in the resistance to HER family receptor targeted therapyIntravital imaging of SRF and Notch signalling identifies a key role for EZH2 in invasive melanoma cellsNotch signalling pathway as an oncogenic factor involved in cancer developmentRare missense neuronal cadherin gene (CDH2) variants in specific obsessive-compulsive disorder and Tourette disorder phenotypesSystems Analysis of Adaptive Responses to MAP Kinase Pathway Blockade in BRAF Mutant Melanoma.The novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanomaγ-Secretase inhibitor enhances antitumour effect of radiation in Notch-expressing lung cancerSuppression subtractive hybridization profiles of radial growth phase and metastatic melanoma cell lines reveal novel potential targets.PIM2 Induced COX-2 and MMP-9 expression in macrophages requires PI3K and Notch1 signalingNotch1 activation is a poor prognostic factor in patients with gastric cancer.Dormancy of metastatic melanomaIdentification of E-selectin as a novel target for the regulation of postnatal neovascularization: implications for diabetic wound healing.The regulation of miRNA-211 expression and its role in melanoma cell invasiveness.C3orf21 ablation promotes the proliferation of lung adenocarcinoma, and its mutation at the rs2131877 locus may serve as a susceptibility marker.Identification of novel targets of CSL-dependent Notch signaling in hematopoiesisDistinct expression profiles of Notch-1 protein in human solid tumors: Implications for development of targeted therapeutic monoclonal antibodiesRecent advances on skin-resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti-aging and cancer therapies.Notch-1 inhibition by Withaferin-A: a therapeutic target against colon carcinogenesis.Genomic events associated with progression of pleural malignant mesothelioma.Notch inhibitors for cancer treatment.A Notch1-neuregulin1 autocrine signaling loop contributes to melanoma growth.The chick embryo as an experimental system for melanoma cell invasion.Akt1 mediates neuronal differentiation in zebrafish via a reciprocal interaction with notch signalingHypoxia, melanocytes and melanoma - survival and tumor development in the permissive microenvironment of the skin.Targeting Nodal in malignant melanoma cells.Role of Notch and its oncogenic signaling crosstalk in breast cancer.Mastermind-like transcriptional co-activators: emerging roles in regulating cross talk among multiple signaling pathways.Phase 2 study of RO4929097, a gamma-secretase inhibitor, in metastatic melanoma: SWOG 0933.Identification and validation of Notch pathway activating compounds through a novel high-throughput screening method.Disparity expression of Notch1 in benign and malignant colorectal diseasesThe MEK/ERK pathway promotes NOTCH signalling in pancreatic cancer cells.Vimentin and Notch as biomarkers for breast cancer progressionCrosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specificationMicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanomaHypoxia promotes uveal melanoma invasion through enhanced Notch and MAPK activationPrediction of signaling cross-talks contributing to acquired drug resistance in breast cancer cells by Bayesian statistical modeling
P2860
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P2860
Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Notch1 signaling promotes prim ...... ulating N-cadherin expression.
@en
type
label
Notch1 signaling promotes prim ...... ulating N-cadherin expression.
@en
prefLabel
Notch1 signaling promotes prim ...... ulating N-cadherin expression.
@en
P2093
P1433
P1476
Notch1 signaling promotes prim ...... ulating N-cadherin expression.
@en
P2093
Chelsea C Pinnix
Klara Balint
Patricia Brafford
Ruihua Qiu
Zhao-Jun Liu
P304
P356
10.1158/0008-5472.CAN-05-3589
P407
P577
2006-04-01T00:00:00Z