SLX4 Prevents GEN1-Dependent DSBs During DNA Replication Arrest Under Pathological Conditions in Human Cells.

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Phosphorylation by CK2 regulates MUS81/EME1 in mitosis and after replication stress.

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Q54977571-52661943-27D8-4633-B3A2-B4E1829EAE3B

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SLX4 Prevents GEN1-Dependent DSBs During DNA Replication Arrest Under Pathological Conditions in Human Cells.

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SLX4 Prevents GEN1-Dependent D ...... cal Conditions in Human Cells.

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SLX4 Prevents GEN1-Dependent D ...... cal Conditions in Human Cells.

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SLX4 Prevents GEN1-Dependent D ...... cal Conditions in Human Cells.

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P1476

SLX4 Prevents GEN1-Dependent D ...... cal Conditions in Human Cells.

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Annapaola Franchitto

http://www.w3.org/2001/XMLSchema#string

Eva Malacaria

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P2860

Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases

Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions

Mutations of the SLX4 gene in Fanconi anemia

GEN1/Yen1 and the SLX4 complex: Solutions to the problem of Holliday junction resolution.

Mechanism of Holliday junction resolution by the human GEN1 protein

Structure-specific DNA endonuclease Mus81/Eme1 generates DNA damage caused by Chk1 inactivation.

Identification and characterization of the human mus81-eme1 endonuclease.

Survival of the replication checkpoint deficient cells requires MUS81-RAD52 function.

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srep44464

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44464

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scholarly article

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10.1038/SREP44464

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English

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Pietro Pichierri

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2017-03-14T00:00:00Z

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1084132354

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28290553

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5349550

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SLX4 Prevents GEN1-Dependent DSBs During DNA Replication Arrest Under Pathological Conditions in Human Cells.

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P2860

P2860

SLX4 Prevents GEN1-Dependent DSBs During DNA Replication Arrest Under Pathological Conditions in Human Cells.

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P1476

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P2860

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P1433

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P407

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P698

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