Semisynthetic homoharringtonine induces apoptosis via inhibition of protein synthesis and triggers rapid myeloid cell leukemia-1 down-regulation in myeloid leukemia cells.
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ERdj5 sensitizes neuroblastoma cells to endoplasmic reticulum stress-induced apoptosisSeed Oil of Brucea javanica Induces Apoptotic Death of Acute Myeloid Leukemia Cells via Both the Death Receptors and the Mitochondrial-Related PathwaysCancer wars: natural products strike backAltering chemosensitivity by modulating translation elongationDeficiency of suppressor enhancer Lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethalityPhase 2 study of subcutaneous omacetaxine mepesuccinate after TKI failure in patients with chronic-phase CML with T315I mutation.Phase 2 study of subcutaneous omacetaxine mepesuccinate for chronic-phase chronic myeloid leukemia patients resistant to or intolerant of tyrosine kinase inhibitors.Omacetaxine mepesuccinate: a new treatment option for patients with chronic myelogenous leukemia.Investigation into omacetaxine solution stability for in vitro study.Identification of genetic variants or genes that are associated with Homoharringtonine (HHT) response through a genome-wide association study in human lymphoblastoid cell lines (LCLs)A comparative proteomic study of Homoharringtonine-induced apoptosis in leukemia K562 cells.Proteostasis regulation at the endoplasmic reticulum: a new perturbation site for targeted cancer therapy.Integrated stress response modulates cellular redox state via induction of cystathionine γ-lyase: cross-talk between integrated stress response and thiol metabolism.Emerging therapeutics targeting mRNA translationHigh-throughput simultaneous screen and counterscreen identifies homoharringtonine as synthetic lethal with von Hippel-Lindau loss in renal cell carcinomaTranslation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributorType I interferons mediate pancreatic toxicities of PERK inhibition.ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo.Differential control of the CCAAT/enhancer-binding protein beta (C/EBPbeta) products liver-enriched transcriptional activating protein (LAP) and liver-enriched transcriptional inhibitory protein (LIP) and the regulation of gene expression during theDual targeting of the cyclin/Rb/E2F and mitochondrial pathways in mantle cell lymphoma with the translation inhibitor silvestrol.Absence of iron-regulatory protein Hfe results in hyperproliferation of retinal pigment epithelium: role of cystine/glutamate exchangerHomoharringtonine for the treatment of chronic myelogenous leukemia.Inhibitory effect of magnetic Fe3O4 nanoparticles coloaded with homoharringtonine on human leukemia cells in vivo and in vitro.Homoharringtonine and omacetaxine for myeloid hematological malignancies.Advances in treatment of chronic myelogenous leukemia--new treatment options with tyrosine kinase inhibitors.The combination effect of homoharringtonine and ibrutinib on FLT3-ITD mutant acute myeloid leukemia.New drugs for chronic myelogenous leukemia.Targeting translation dependence in cancerCell cycle modulatory and apoptotic effects of plant-derived anticancer drugs in clinical use or development.Omacetaxine mepesuccinate (synribo) - newly launched in chronic myeloid leukemia.Omacetaxine mepesuccinate in the treatment of intractable chronic myeloid leukemia.Omacetaxine mepesuccinate in chronic myeloid leukemia.ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner.A safety evaluation of omacetaxine mepesuccinate for the treatment of chronic myeloid leukemia.Homoharringtonine as a backbone drug for the treatment of newly diagnosed pediatric acute myeloid leukemia: a report from a single institution in China.Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells.Endoplasmic reticulum stress signaling and chemotherapy resistance in solid cancers.A homoharringtonine-based induction regimen for the treatment of elderly patients with acute myeloid leukemia: a single center experience from ChinaLoss of the Atp2c1 secretory pathway Ca(2+)-ATPase (SPCA1) in mice causes Golgi stress, apoptosis, and midgestational death in homozygous embryos and squamous cell tumors in adult heterozygotes.Inhibition of myeloid cell leukemia-1 by tolfenamic acid induces apoptosis in mucoepidermoid carcinoma.
P2860
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P2860
Semisynthetic homoharringtonine induces apoptosis via inhibition of protein synthesis and triggers rapid myeloid cell leukemia-1 down-regulation in myeloid leukemia cells.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Semisynthetic homoharringtonin ...... ion in myeloid leukemia cells.
@en
type
label
Semisynthetic homoharringtonin ...... ion in myeloid leukemia cells.
@en
prefLabel
Semisynthetic homoharringtonin ...... ion in myeloid leukemia cells.
@en
P2093
P1476
Semisynthetic homoharringtonin ...... ion in myeloid leukemia cells.
@en
P2093
Anne-Marie Faussat
Christophe Marzac
Jean-Pierre Marie
Ollivier Legrand
Patricia Majdak
Ruoping Tang
Sabine Dubrulle
Zora Marjanovic
P304
P356
10.1158/1535-7163.MCT-05-0164
P577
2006-03-01T00:00:00Z