Caspase cleaved presenilin-1 is part of active gamma-secretase complexes.

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Cross-linking of cell surface amyloid precursor protein leads to increased β-amyloid peptide production in hippocampal neurons: implications for Alzheimer's disease.γ-Secretase complexes containing caspase-cleaved presenilin-1 increase intracellular Aβ(42) /Aβ(40) ratio.

P2860

Q36517026-F2EA5D8E-0B7D-4047-9A65-A26835E86F79 Q39545955-F3E41F5E-B046-467E-B309-C88727EE2B9C

P2860

Caspase cleaved presenilin-1 is part of active gamma-secretase complexes.

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http://www.wikidata.org/entity/Q40304488

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2006 nî lūn-bûn

@nan

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

2006年论文

@zh

2006年论文

@zh-cn

name

Caspase cleaved presenilin-1 is part of active gamma-secretase complexes.

@en

type

Item

label

Caspase cleaved presenilin-1 is part of active gamma-secretase complexes.

@en

prefLabel

Caspase cleaved presenilin-1 is part of active gamma-secretase complexes.

@en

P1476

Caspase cleaved presenilin-1 is part of active gamma-secretase complexes.

@en

P2093

Bogdan O Popescu

http://www.w3.org/2001/XMLSchema#string

Camilla A Hansson

http://www.w3.org/2001/XMLSchema#string

Hanna Laudon

http://www.w3.org/2001/XMLSchema#string

Laurentiu M Popescu

http://www.w3.org/2001/XMLSchema#string

Maria Ankarcrona

http://www.w3.org/2001/XMLSchema#string

P2860

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions.

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

Release of a membrane-bound death domain by gamma-secretase processing of the p75NTR homolog NRADD

Mice lacking both presenilin genes exhibit early embryonic patterning defects

Differential expression of rat brain caspase family proteins during development and aging

Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-Like protein 2

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

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356-364

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scholarly article

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10.1111/J.1471-4159.2006.03735.X

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P407

English

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http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Angel Cedazo-Minguez

Bengt Winblad

P577

2006-03-15T00:00:00Z

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P5875

7238339

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P698

16539675

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Caspase cleaved presenilin-1 is part of active gamma-secretase complexes.

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P2860

P2860

Caspase cleaved presenilin-1 is part of active gamma-secretase complexes.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698