Membrane-anchored inhibitory peptides capture human immunodeficiency virus type 1 gp41 conformations that engage the target membrane prior to fusion.
about
P2X1 Receptor Antagonists Inhibit HIV-1 Fusion by Blocking Virus-Coreceptor InteractionsDissociation of the trimeric gp41 ectodomain at the lipid–water interface suggests an active role in HIV-1 Env-mediated membrane fusionRole of Abl kinase and the Wave2 signaling complex in HIV-1 entry at a post-hemifusion stepMembrane-anchored HIV-1 N-heptad repeat peptides are highly potent cell fusion inhibitors via an altered mode of actionA monoclonal Fab derived from a human nonimmune phage library reveals a new epitope on gp41 and neutralizes diverse human immunodeficiency virus type 1 strains.Sequestering of the prehairpin intermediate of gp41 by peptide N36Mut(e,g) potentiates the human immunodeficiency virus type 1 neutralizing activity of monoclonal antibodies directed against the N-terminal helical repeat of gp41Affinity maturation by targeted diversification of the CDR-H2 loop of a monoclonal Fab derived from a synthetic naïve human antibody library and directed against the internal trimeric coiled-coil of gp41 yields a set of Fabs with improved HIV-1 neutEfficient entry inhibition of human and nonhuman primate immunodeficiency virus by cell surface-expressed gp41-derived peptides.GPI-anchored single chain Fv--an effective way to capture transiently-exposed neutralization epitopes on HIV-1 envelope spike.Virus-cell and cell-cell fusion mediated by the HIV-1 envelope glycoprotein is inhibited by short gp41 N-terminal membrane-anchored peptides lacking the critical pocket domain.A novel real-time CTL assay to measure designer T-cell function against HIV Env(+) cells.Complete dissociation of the HIV-1 gp41 ectodomain and membrane proximal regions upon phospholipid bindingInsights into the Conformation of the Membrane Proximal Regions Critical to the Trimerization of the HIV-1 gp41 Ectodomain Bound to Dodecyl Phosphocholine Micelles.Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino TerminusSphingopeptides: dihydrosphingosine-based fusion inhibitors against wild-type and enfuvirtide-resistant HIV-1Mutations in gp120 contribute to the resistance of human immunodeficiency virus type 1 to membrane-anchored C-peptide maC46.Common principles and intermediates of viral protein-mediated fusion: the HIV-1 paradigm.Computer-Aided Approaches for Targeting HIVgp41.Extolling the benefits of molecular therapeutic lipidation.Glycosyl Phosphatidylinositol-Anchored C34 Peptide Derived From Human Immunodeficiency Virus Type 1 Gp41 Is a Potent Entry Inhibitor.HIV Entry and Its Inhibition by Bifunctional Antiviral ProteinsGenetic Strategies for HIV Treatment and Prevention
P2860
Q27321418-08B5C09F-2B11-4AA9-85AD-20115A24674CQ27681827-E5319A47-25C3-4D19-BBC2-10F1F33F5434Q28474499-FECADEF5-E187-481D-ABF8-2A6DC8906FABQ28475682-E63CF36B-C99F-4AA6-8CDC-7B70A7F1C182Q33300529-B42DE7C5-06DC-4365-B33A-191C8961C743Q33356323-D12B59B9-10F0-40EA-97E0-AB6E7C2B8F2FQ33495440-CC324FCB-F9FB-449A-9AF7-8757E556D9AEQ33822282-C91B501D-CEA2-4820-A322-E4E1F66E9D7AQ34221625-7F5FEE8E-AA5D-45CF-B58F-7D6E3545A012Q34281656-B03B2C7F-2A42-4466-AB8C-1259C3EEC228Q35052987-10129830-B67B-4535-8918-470CBA7382FAQ35434452-1BA986F6-CF66-4655-8FB5-5361F10C2EFCQ36101299-8A7B1AF0-26F2-4F2F-8979-C532FD2B78EDQ36195192-28166BB4-03C1-4037-880F-A87A5F598CF3Q36329809-B1011967-DFD2-411F-BD5D-7948486E58D0Q37192248-9378CF34-ED77-44CF-A546-AE03E35D8CB2Q37348882-09BA0BF3-BF1D-43C4-A4FD-2DF875895BBBQ38111393-86BA7AE4-342A-4278-8B7E-33CDDE3B67EBQ38114781-DAF6044A-7681-41B7-ACEA-58B87D841530Q40683638-3990645A-E102-4793-8C84-A04D8927C2D4Q58555325-CFDDAE81-0480-4130-84C6-32AB0C8435B3Q58604627-5D5C74E8-6408-4D2E-9824-FDF5CC0B8D43
P2860
Membrane-anchored inhibitory peptides capture human immunodeficiency virus type 1 gp41 conformations that engage the target membrane prior to fusion.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Membrane-anchored inhibitory p ...... rget membrane prior to fusion.
@en
type
label
Membrane-anchored inhibitory p ...... rget membrane prior to fusion.
@en
prefLabel
Membrane-anchored inhibitory p ...... rget membrane prior to fusion.
@en
P2860
P1433
P1476
Membrane-anchored inhibitory p ...... rget membrane prior to fusion.
@en
P2093
Gregory B Melikyan
Marc Egelhofer
P2860
P304
P356
10.1128/JVI.80.7.3249-3258.2006
P407
P577
2006-04-01T00:00:00Z