Mithramycin selectively inhibits collagen-alpha 1(I) gene expression in human fibroblast.
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The loss of sarco/endoplasmic reticulum calcium transport ATPase 3 expression is an early event during the multistep process of colon carcinogenesisMolecular Insight into Substrate Recognition and Catalysis of Baeyer–Villiger Monooxygenase MtmOIV, the Key Frame-Modifying Enzyme in the Biosynthesis of Anticancer Agent MithramycinSp1 and Smad proteins cooperate to mediate transforming growth factor-beta 1-induced alpha 2(I) collagen expression in human glomerular mesangial cellsA histone deacetylase 4/myogenin positive feedback loop coordinates denervation-dependent gene induction and suppressionRegulation of histone deacetylase 4 expression by the SP family of transcription factors.Potential methods to prevent interstitial fibrosis in renal disease.Myocardin-related transcription factor-A complexes activate type I collagen expression in lung fibroblasts.Epigenetic modulation of the protein kinase A RIIα (PRKAR2A) gene by histone deacetylases 1 and 2 in human smooth muscle cells.Sp1 is involved in Akt-mediated induction of VEGF expression through an HIF-1-independent mechanism.Extracellular matrix synthesis in vascular disease: hypertension, and atherosclerosis.Intra- and intermolecular triplex DNA formation in the murine c-myb proto-oncogene promoter are inhibited by mithramycin.Ring-Sp1 decoy oligonucleotide effectively suppresses extracellular matrix gene expression and fibrosis of rat kidney induced by unilateral ureteral obstruction.Inhibition of p53-mediated transcriptional responses by mithramycin A.Transforming growth factor beta1 induces alphavbeta3 integrin expression in human lung fibroblasts via a beta3 integrin-, c-Src-, and p38 MAPK-dependent pathway.Sp1 is required for the early response of alpha2(I) collagen to transforming growth factor-beta1.Inhibition of collagen gene expression in systemic sclerosis dermal fibroblasts by mithramycin.Inhibition of basal and transforming growth factor-beta-induced stimulation of COL1A1 transcription by the DNA intercalators, mitoxantrone and WP631, in cultured human dermal fibroblasts.Downregulation of protease-activated receptor-1 in human lung fibroblasts is specifically mediated by the prostaglandin E receptor EP2 through cAMP elevation and protein kinase A.
P2860
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P2860
Mithramycin selectively inhibits collagen-alpha 1(I) gene expression in human fibroblast.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Mithramycin selectively inhibits collagen-alpha 1(I) gene expression in human fibroblast.
@en
type
label
Mithramycin selectively inhibits collagen-alpha 1(I) gene expression in human fibroblast.
@en
prefLabel
Mithramycin selectively inhibits collagen-alpha 1(I) gene expression in human fibroblast.
@en
P2093
P2860
P356
P1476
Mithramycin selectively inhibits collagen-alpha 1(I) gene expression in human fibroblast.
@en
P2093
Brenner DA
Dierbach H
Herrmann F
Mertelsmann R
P2860
P304
P356
10.1172/JCI116914
P407
P577
1993-12-01T00:00:00Z