Misfolding pathways of the prion protein probed by molecular dynamics simulations.
about
Full-length prion protein aggregates to amyloid fibrils and spherical particles by distinct pathways.Nanopore analysis of wild-type and mutant prion protein (PrP(C)): single molecule discrimination and PrP(C) kinetics.Structural and dynamic properties of the human prion protein.The intrinsic helical propensities of the helical fragments in prion protein under neutral and low pH conditions: a replica exchange molecular dynamics study.Comparative analysis of essential collective dynamics and NMR-derived flexibility profiles in evolutionarily diverse prion proteinsProtective V127 prion variant prevents prion disease by interrupting the formation of dimer and fibril from molecular dynamics simulations.The consequences of pathogenic mutations to the human prion protein.Differential stability of the bovine prion protein upon urea unfoldingBeta-sheet containment by flanking prolines: molecular dynamic simulations of the inhibition of beta-sheet elongation by proline residues in human prion protein.Molecular dynamics simulations and novel drug discovery.Toward quantitative estimates of binding affinities for protein-ligand systems involving large inhibitor compounds: a steered molecular dynamics simulation route.Essential Role of Hydration in Aggregation of Misfolded Prion Proteins: Quantification by Molecular Theory of SolvationStructural basis for the complete resistance of the human prion protein mutant G127V to prion disease
P2860
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P2860
Misfolding pathways of the prion protein probed by molecular dynamics simulations.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Misfolding pathways of the prion protein probed by molecular dynamics simulations.
@en
type
label
Misfolding pathways of the prion protein probed by molecular dynamics simulations.
@en
prefLabel
Misfolding pathways of the prion protein probed by molecular dynamics simulations.
@en
P2093
P2860
P1433
P1476
Misfolding pathways of the prion protein probed by molecular dynamics simulations.
@en
P2093
Alessandro Barducci
Piero Procacci
Riccardo Chelli
Vincenzo Schettino
P2860
P304
P356
10.1529/BIOPHYSJ.104.049882
P407
P577
2004-11-19T00:00:00Z