Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells.
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Chronic exposure to carbon nanotubes induces invasion of human mesothelial cells through matrix metalloproteinase-2Phellinus linteus suppresses growth, angiogenesis and invasive behaviour of breast cancer cells through the inhibition of AKT signallingOsteopontin (OPN) is an important protein to mediate improvements in the biocompatibility of C ion-implanted silicone rubberuPAR induces expression of transforming growth factor β and interleukin-4 in cancer cells to promote tumor-permissive conditioning of macrophages.Identification of osteopontin-dependent signaling pathways in a mouse model of human breast cancer.The RGD domain of human osteopontin promotes tumor growth and metastasis through activation of survival pathwaysPatterns of gene expression associated with Pten deficiency in the developing inner ear.RNA aptamer blockade of osteopontin inhibits growth and metastasis of MDA-MB231 breast cancer cells.Versican G3 promotes mouse mammary tumor cell growth, migration, and metastasis by influencing EGF receptor signaling.Hepatitis B virus X protein drives multiple cross-talk cascade loops involving NF-κB, 5-LOX, OPN and Capn4 to promote cell migration.The role of versican G3 domain in regulating breast cancer cell motility including effects on osteoblast cell growth and differentiation in vitro - evaluation towards understanding breast cancer cell bone metastasis.Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): multifunctional proteins in cancerInduction of osteopontin expression by nicotine and cigarette smoke in the pancreas and pancreatic ductal adenocarcinoma cellsOsteopontin gene expression determines spontaneous metastatic performance of orthotopic human breast cancer xenografts.Osteopontin regulates ubiquitin-dependent degradation of Stat1 in murine mammary epithelial tumor cells.Pleural fluid osteopontin, vascular endothelial growth factor, and urokinase-type plasminogen activator levels as predictors of pleurodesis outcome and prognosticators in patients with malignant pleural effusion: a prospective cohort studyRole of integrins in regulating proteases to mediate extracellular matrix remodelingThe fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis.Osteopontin: an emerging therapeutic target for anticancer therapy.Urokinase-type Plasminogen Activator (uPA) is Inhibited with QLT0267 a Small Molecule Targeting Integrin-linked Kinase (ILK)Contributions of integrin-linked kinase to breast cancer metastasis and tumourigenesis.Sustained inhibition of PKCα reduces intravasation and lung seeding during mammary tumor metastasis in an in vivo mouse model.cRGD inhibits vasculogenic mimicry formation by down-regulating uPA expression and reducing EMT in ovarian cancer.Lapatinib-loaded human serum albumin nanoparticles for the prevention and treatment of triple-negative breast cancer metastasis to the brain.Expression of a prometastatic splice variant of osteopontin, OPNC, in human pancreatic ductal adenocarcinoma.The role of osteopontin in inflammatory processesBone sialoprotein and osteopontin in bone metastasis of osteotropic cancersIntegrin-linked kinase 1: role in hormonal cancer progression.Architecture and the extracellular matrix: the still unappreciated components of the adipose tissue.Osteopontin: a potentially important therapeutic target in cancer.Osteopontin as a therapeutic target for cancer.Osteopontin -- a promising biomarker for cancer therapy.Osteopontin: its potential role in cancer of children and young adults.Human osteopontin: Potential clinical applications in cancer (Review)Loss of MMP-2 in murine osteoblasts upregulates osteopontin and bone sialoprotein expression in a circuit regulating bone homeostasis.Conjugation of cRGD peptide to chlorophyll a based photosensitizer (HPPH) alters its pharmacokinetics with enhanced tumor-imaging and photosensitizing (PDT) efficacy.Osteopontin at the Crossroads of Inflammation and Tumor Progression.Overexpression of integrin-linked kinase promotes lung cancer cell migration and invasion via NF-κB-mediated upregulation of matrix metalloproteinase-9.Inhibition of Necl-5 (CD155/PVR) reduces glioblastoma dispersal and decreases MMP-2 expression and activity.The Role of Mediators of Cell Invasiveness, Motility, and Migration in the Pathogenesis of Silent Corticotroph Adenomas
P2860
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P2860
Integrin-linked kinase regulates osteopontin-dependent MMP-2 and uPA expression to convey metastatic function in murine mammary epithelial cancer cells.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Integrin-linked kinase regulat ...... mmary epithelial cancer cells.
@en
type
label
Integrin-linked kinase regulat ...... mmary epithelial cancer cells.
@en
prefLabel
Integrin-linked kinase regulat ...... mmary epithelial cancer cells.
@en
P2093
P2860
P356
P1433
P1476
Integrin-linked kinase regulat ...... mmary epithelial cancer cells.
@en
P2093
Chengjiang Gao
Hongtao Guo
Paul C Kuo
Philip Y Wai
Zhiyong Mi
P2860
P304
P356
10.1093/CARCIN/BGI352
P407
P577
2006-02-12T00:00:00Z